Products Ciprofibrate was commercially available in many countries in capsule form (Hyperlipen, off label). It was approved in 1993 and has not been available since 2013. Structure and properties Ciprofibrate (C13H14Cl2O3, Mr = 289.2 g/mol) is a racemate and a phenoxyisobutyric acid derivative. It exists as a white to pale yellow powder that is practically … Ciprofibrate
Products Fluvastatin is commercially available in the form of capsules and sustained-release generic tablets (generics). It has been approved in many countries since 1993. Sales of the original Lescol were discontinued by Novartis in 2018. Structure and properties Fluvastatin (C24H26FNO4, Mr = 411.5 g/mol) is present in drugs as fluvastatin sodium, a white or pale … Fluvastatin
Products Etofibrate is commercially available in the form of sustained-release capsules (Lipo-Merz retard). The drug is no longer registered in many countries. Structure and properties Etofibrate (C18H18ClNO5, Mr = 363.8 g/mol is a diester of clofibric acid and nicotinic acid linked via ethylene glycol. Effects Etofibrate (ATC C10AB09) is lipid-lowering. It lowers elevated cholesterol and … Etofibrate
Products Pitavastatin is commercially available in the form of film-coated tablets (Livazo). It was first approved in many countries in July 2012. In Japan, it has been on the market since 2003, and it is also available in other countries such as the United States and Germany. Structure and properties Pitavastatin (C25H24FNO4, Mr = 421.5 … Pitavastatin
Products Bezafibrate is commercially available in the form of sustained-release tablets (Cedur retard). It has been approved in many countries since 1979. Structure and properties Bezafibrate (C19H20ClNO4, Mr = 361.8 g/mol) lies as a white crystalline powder that is practically insoluble in water. Effects Bezafibrate (ATC C10AB02) primarily lowers elevated blood triglyceride levels. It has … Bezafibrate
Products Atorvastatin is commercially available in the form of film-coated tablets (Sortis, generic, auto-generic). It has been approved in many countries since 1997. Atorvastatin is also available as a fixed combination with ezetimibe; see Atorvastatin and Ezetimibe. Structure and Properties Atorvastatin (C33H35FN2O5, Mr = 558.64 g/mol) is present in drugs as atorvastatin calcium trihydrate, (atorvastatin)2– … Atorvastatin
Products Simvastatin is commercially available in the form of film-coated tablets (Zocor, generics). It is also combined fixed with ezetimibe (Inegy, generic). Simvastatin has been approved in many countries since 1990. Structure and properties Simvastatin (C25H38O5, Mr = 418.6 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a … Simvastatin: Drug Effects, Side Effects, Dosage and Uses
Gemfibrozil is a medical agent that belongs to the so-called fibrates. As such, gemfibrozil is administered to treat diseases as well as disorders of lipid metabolism. It can also be taken for dietary purposes. Through this, weight loss can be achieved. What is gemfibrozil? Gemfibrozil is an orally taken fibrate. The term fibrate covers various … Gemfibrozil: Effects, Uses & Risks
The term hyperlipidemia is composed of “hyper” (too much, excessive), “lipid” (fat) and “-emia” (in the blood) and describes an excess of fats in the blood. In common parlance, the term “high blood lipid levels” is also used. Various fats are found in the blood: neutral fats, cholesterol and lipoproteins. Lipoproteins are protein particles that … Hyperlipidemia
Symptoms The blood fats are divided into “good” and “bad” fats. The HDL cholesterol is the “good” cholesterol. The most important representative of the “bad” fats is the LDL cholesterol. Like all other “bad” fats, it increases the risk of atherosclerosis (hardening of the arteries). Unfortunately, arteriosclerosis remains asymptomatic for a very long time. Only … Symptoms | Hyperlipidemia
Diagnosis The diagnosis of hyperlipidemia is made by taking a blood sample. Patients should be fasting for 12 hours before taking the blood sample in order not to falsify the blood lipid values by ingested food. A screening is carried out by the family doctor from the age of 35. The screening includes the determination … Diagnosis | Hyperlipidemia
