Products Nalmefene is commercially available in the form of film-coated tablets (Selincro). It was registered in many countries in 2014. Structure and properties Nalmefene (C21H25NO3, Mr = 339.4 g/mol) is structurally closely related to naltrexone, from which it is derived. In the drug product, it is present as nalmefene hydrochloride and dihydrate, a white crystalline … Nalmefene
Products Antifungal products are commercially available as creams, ointments, powders, solutions, tablets, capsules, and injectables, among others. Structure and properties The antifungal agents are a structurally heterogeneous class of agents. However, several groups can be identified within the antifungals, such as the azole antifungals and the allylamines (see below). Effects Antifungals have antifungal, fungistatic, or … Antifungals
Symptoms Typical symptoms of agranulocytosis include fever, chills, feeling ill, tonsillitis, sore throat, difficulty swallowing, and lesions and bleeding of the oral, nasal, pharyngeal, genital, or anal mucosa. The disease can lead to dangerous infections and blood poisoning and, if left untreated, can relatively often be fatal. Agranulocytosis usually occurs rarely to very rarely as … Agranulocytosis Symptoms and Treatment
Products Azole antifungals are approved in many countries for both topical and systemic treatment. They are available in numerous dosage forms-including creams, an oral gel, powders, sprays, tablets, capsules, injectables, vaginal creams, and vaginal tablets. The first azole antifungal came on the market in the 1950s. Structure and properties The name azole refers to heterocycles … Azole Antifungals
Symptoms Intertrigo (Latin for “rubbed sore”) is a common inflammatory skin condition that occurs on opposite skin surfaces in skin folds. It is initially manifested by a mild to severe redness that is approximately mirror image on both sides of the skin fold. It is often accompanied by itching, rash, burning sensation and pain. Papules … Intertrigo
Products Irbesartan is commercially available in the form of film-coated tablets as a monopreparation (Aprovel, generic) and as a fixed combination with hydrochlorothiazide (Co-Aprovel). It has been approved in many countries since 1997. Generics entered the market in many countries in August 2012. Generic versions of the combination preprinted with hydrochlorothiazide went on sale in … Irbesartan
Products Fluvastatin is commercially available in the form of capsules and sustained-release generic tablets (generics). It has been approved in many countries since 1993. Sales of the original Lescol were discontinued by Novartis in 2018. Structure and properties Fluvastatin (C24H26FNO4, Mr = 411.5 g/mol) is present in drugs as fluvastatin sodium, a white or pale … Fluvastatin
Products Voriconazole is commercially available as film-coated tablets, powder for the preparation of an infusion solution, and powder for the preparation of a suspension (Vfend, generics). It has been approved in many countries since 2002. Structure and properties Voriconazole (C16H14F3N5O, Mr = 349.3 g/mol) exists as a white powder that is very sparingly soluble in … Voriconazole
Symptoms Pityriasis versicolor is a skin disorder that occurs primarily on areas with high sebum production, such as the back, chest, upper arms, shoulders, armpits, neck, face, and scalp. Round to oval hyper- or hypopigmented patches occur. The skin is slightly thickened, scaly, and sometimes mildly itchy. The patches may be colored, for example, pink, … Pityriasis Versicolor: Medicinal Uses
Symptoms Calf lichen is a localized fungal infection of the skin with vesicles, papules, and pustules. The skin is pale on the inside and surrounded by a red ring on the outside. A strong inflammation is typical. The scalp, face, nails, beard and exposed skin areas such as the arms can be affected. The infection … Calf Lichen
Products Fluconazole is commercially available in capsule form, as a powder for suspension, and as an infusion solution (Diflucan, generic). It has been approved in many countries since 1989. Structure and properties Fluconazole (C13H12F2N6O, Mr = 306.3 g/mol) is a fluorinated triazole derivative. It exists as a white, crystalline and hygroscopic powder that is sparingly … Fluconazole
Definition and examples The duration of therapy or treatment defines the period of time during which a drug is administered preventively or therapeutically. The shortest duration of therapy occurs with a single dose. This involves a single administration of a drug without repetition. An example of this is the antifungal drug fluconazole for the treatment … Duration of Therapy
