Products Copper is commercially available in multivitamin preparations, dietary supplements, and ointments and solutions, among other products. Hormone-free intrauterine devices (known as “coils”) or copper chains are also approved for contraception. These are medical devices and not drugs. Structure and properties Copper (cuprum, Cu, atomic number 29) is a soft and easily workable transition and … Copper
Products 2-Phenylphenol is commercially available as a drug in combination with other disinfectants as a solution (Kodan). Structure and properties 2-Phenylphenol (C12H10O, Mr = 170.21 g/mol) is a phenol substituted at position 2 with a benzene ring. It exists as a white powder or solid. Effects 2-Phenylphenol has antimicrobial (antibacterial, antifungal) and antiviral properties. The … 2-Phenylphenol
Products Amorolfine is commercially available for the treatment of a nail fungus as a nail polish (Loceryl, Curanel, 5%, generic). It has been approved in many countries since 1991. Curanel was released in April 2011 and, unlike Loceryl, is available without a doctor’s prescription. It is also sold as Curanail in other countries. In 2014, … Amorolfine
Products Nystatin is commercially available as a monopreparation as an oral suspension (Mycostatin, Multilind). Combination preparations are also available. Nystatin has been approved in many countries since 1967. Structure and properties Nystatin (C47H75NO17, Mr = 926 g/mol) is a fungicidal substance obtained from certain strains of by fermentation. It consists largely of tetraenes, the major … Nystatin: Drug Effects, Side Effects, Dosage and Uses
Products Octenidine is commercially available in many countries as colorless and colored solutions, gargle solutions, and wound gels (Octenisept, Octeniderm, Octenimed), among others. It has been approved since 1990. Structure and properties Octenidine (C36H62N4, Mr = 550.9 g/mol) is present in the drug as octenidine dihydrochloride, a colorless liquid. It is a cationic, surface-active agent. … Octenidine
Products Caspofungin must be administered as an infusion solution because of its low oral bioavailability (Cancidas, generics). It has been approved in many countries since 2002 and was the first member of the echinocandins. Structure and properties Caspofungin is present in drugs as caspofungin diacetate (C52H88N10O15 – 2C2H4O2, Mr = 1213.42 g/mol), a hygroscopic white … Caspofungin
Products Polihexanide is commercially available as a solution and concentrate (Lavasept). It has been approved in many countries since 1991. Structure and properties Polihexanide (C8H19N5, Mr = 185.3 g/mol) is a biguanide derivative. Effects Polihexanide (ATC D08AC05) has bactericidal and fungicidal properties. Indications For antiseptic wound treatment and prophylaxis of bone and soft tissue infections. … Polihexanide
Products Anidulafungin is commercially available as a powder for the preparation of an infusion solution (Ecalta, generics). It has been approved in many countries since 2009. Structure and properties Anidulafungin (C58H73N7O17, Mr = 1140.3 g/mol) is a cyclic lipopeptide. It is a semisynthetic echinocandin obtained from a fermentation product of . It exists as a … Anidulafungin
Products Isavuconazonium sulfate is commercially available as a powder for a concentrate for the preparation of an infusion solution and in capsule form (Cresemba). It was approved in the US and EU in 2015 and in many countries in 2017. Structure and properties Isavuconazonium sulfate (C35H35F2N8O5S+ – HSO4– Mr = 814.8 g/mol) is a prodrug … Isavuconazonium Sulfate
Products Antifungal products are commercially available as creams, ointments, powders, solutions, tablets, capsules, and injectables, among others. Structure and properties The antifungal agents are a structurally heterogeneous class of agents. However, several groups can be identified within the antifungals, such as the azole antifungals and the allylamines (see below). Effects Antifungals have antifungal, fungistatic, or … Antifungals
Products In 2009, a water-soluble varnish containing 8% ciclopirox was approved in many countries for the treatment of nail fungus, which is applied once daily (Ciclopoli). It went on sale in January 2011. In many countries, ciclopirox 8% had already been approved for the treatment of nail fungus for a number of years, in France … Ciclopirox against Nail Fungus
Products Undecylenic acid is commercially available in many countries as an ointment (Undex, combination preparation). Solutions and creams are also available in some countries. Undecylenic acid has been used medicinally for many decades. Undex ointment has been approved in many countries since 1951. Structure and properties Undecylenic acid (C11H20O2, Mr = 184.3 g/mol) exists as … Undecylenic Acid
