Products Desloratadine is commercially available as 5 mg film-coated tablets and as a solution (Aerius, generics). It has been approved in many countries since 2001. The syrup was replaced in 2011 by a solution that is sugar- and dye-free. The concentration remains identical (0.5 mg/ml). The fixed combination with pseudoephedrine is not yet available in … Desloratadine
Products Oxycodone is commercially available in the form of sustained-release tablets, capsules, melting tablets, as an injectable, and drops (including Oxycontin, Oxynorm, and generics). It has been used medicinally for decades. In the U.S., it is also used as a fix in combination with other analgesics such as acetaminophen (e.g., Percocet). Oxycodone is also available … Oxycodone: Drug Effects, Side Effects, Dosage and Uses
Why is the distribution of medicines discontinued? Drugs are subject to a product life cycle. They are discovered, patented, developed, approved, marketed and, in some circumstances, withdrawn from the market years to decades later. Often, distribution is discontinued due to commercial considerations. For example, the cost of approval and production exceeds the revenue from sales. … Market Withdrawal of Drugs
Products Mood stabilizers are commercially available in the form of tablets, dispersible tablets, and solutions, among others. The best-known active ingredient in this group is lithium. Structure and properties Mood stabilizers are organic molecules (antiepileptic drugs) and salts (lithium). Effects The agents have mood-stabilizing properties, meaning that they are active against depressive and manic episodes, … Mood Stabilizer
Products Salbutamol is commercially available as a metered-dose inhaler, inhalation solution, diskus, syrup, infusion concentrate, and solution for injection (Ventolin, generics). It has been approved in many countries since 1972 and is also known as albuterol in English-speaking countries. Salbutamol is the precursor of salmeterol and vilanterol (all GlaxoSmithKline). Structure and properties Salbutamol (C13H21NO3, Mr … Salbutamol: Drug Effects, Side Effects, Dosage and Uses
Products Alprazolam is commercially available as tablets, sustained-release tablets, and sublingual tablets (Xanax, generics). It has been approved in many countries since 1980. “Xanax” is a palindrome and remains the same when read forwards or backwards. Structure and properties Alprazolam (C17H13ClN4, Mr = 308.7 g/mol) exists as a white crystalline powder that is practically insoluble … Alprazolam
Products Naproxen has been approved in many countries since 1975 and is commercially available in the form of film-coated tablets (e.g., Apranax, Proxen, generics). Other dosage forms such as the suppositories and the juice are no longer available. Drugs with a deep dose have been available over the counter since 1999 (Aleve with 200 mg … Naproxen: Drug Effects, Side Effects, Dosage and Uses
Products The selective serotonin reuptake inhibitors (SSRIs) are mainly taken in the form of film-coated tablets or capsules. In addition, other dosage forms such as dispersible tablets, melting tablets and drops are available. Zimelidin was the first to be developed in the 1970s and was approved in the early 1980s. Sales had to be discontinued … Selective Serotonin Reuptake Inhibitor
Products Oxytocin is commercially available as an injectable and nasal spray (syntocinone). It has been approved in many countries since 1956. Generic products are available in many countries. Structure and properties Oxytocin (C43H66N12O12S2, Mr = 1007.2 g/mol) is a cyclic peptide consisting of 9 amino acids (nonapeptide) with a disulfide bridge. The structure of the … Oxytocin Hormone
Products Clarithromycin is commercially available as film-coated tablets, sustained-release tablets, oral suspension, and powder for solution for infusion (Klacid, generics). It has been approved in many countries since 1990. Clarithromycin should not be confused with ciprofloxacin. Structure and properties Clarithromycin (C38H69NO13, Mr = 747.96 g/mol) exists as a white crystalline powder that is practically insoluble … Clarithromycin
Products Clavulanic acid is sold exclusively in combinations with antibiotic amoxicillin. In addition to the original Augmentin, numerous generics are also available. Structure and properties Clavulanic acid (C8H9NO5, Mr = 199.16 g/mol) is present in drugs as potassium clavulanate, the potassium salt of clavulanic acid. Potassium clavulanate is a white, crystalline, hygroscopic powder that is … Clavulanic Acid
Sucralfate is the name of a drug used to treat stomach and duodenal ulcers. The drug builds up a protective layer on the mucous membrane of the upper digestive region. What is sucralfate? Sucralfate is an aluminum salt of sucrose sulfate. In medicine, the active ingredient is primarily used to treat gastric ulcer (ulcus ventriculi). … Sucralfate: Effects, Uses & Risks
