Abiraterone Acetate

Products Abiraterone is commercially available in the form of film-coated tablets (Zytiga). It has been approved in many countries since 2011. Structure and properties Abiraterone acetate (C26H33NO2, Mr = 391.5 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug and is rapidly biotransformed in the body to … Abiraterone Acetate

Hydrocortisone Soft Ointment

Products and production Hydrocortisone soft ointments are manufactured in 1% or 2% concentrations in pharmacies as extemporaneous preparations. Concentration: 1% 2% Hydrocortisone acetate 1.0 2.0 Soft ointment KA or Unguentum Cordes 99.0 98.0 Recipe DMS The soft ointment consists mostly of viscous kerosene and petrolatum. The manufacturing prescription can be found in the DMS. Effects … Hydrocortisone Soft Ointment

Hydrocortisone Acetate

Products To date, hydrocortisone acetate is the only glucocorticoid approved for self-medication in many countries and is available without a doctor’s prescription. A cream (Dermacalm with dexpanthenol) and a hydrocream (Sanadermil) are available. Hydrocortisone was the first dermocorticoid and was introduced in the 1950s. Structure and properties Hydrocortisone acetate (C23H32O6, Mr = 404.5 g/mol) is … Hydrocortisone Acetate

Methylprednisolone Aceponate

Products Methylprednisolone aceponate has been approved in many countries since 1991 and is commercially available as cream, ointment, and fatty ointment (Advantan). Structure and properties Methylprednisolone aceponate (C27H36O7, Mr = 472.6 g/mol) is a lipophilic and nonhalogenated glucocorticoid that is hydrolyzed in the skin by esterases to the active metabolite 6α-methylprednisolone-17-propionate. Effects Methylprednisolone aceponate (ATC … Methylprednisolone Aceponate

Halcinonide

Products Halcinonide was commercially available as a solution, cream, and fat cream, and was also combined fixedly with urea and salicylic acid (Betacorton, Betacorton S). It was approved in many countries in 1981. It was discontinued from 2018 to 2019. Structure and properties Halcinonide (C24H32ClFO5, Mr = 454.96 g/mol) exists as a white powder that … Halcinonide

Halometasone

Products Halometasone is commercially available as a cream in combination with triclosan (Sicorten plus). It has been approved in many countries since 1983. Structure and properties Halometasone (C22H27ClF2O5, Mr = 444.9 g/mol) is a chlorinated and fluorinated (halogenated) steroid. Effects Halometasone (ATC D07AC12) has anti-inflammatory, antiallergic, and immunosuppressive properties. It is a potent class III … Halometasone

Triamcinolone Acetonide

Products Triamcinolone acetonide is commercially available as suspension for injection (Kenacort-A), solution for injection (Kenacort-A Solubile, Ledermix), crystal suspension (Triamcort Depot), paste (Kenacort-A Orabase), tincture (Kenacort-A + salicylic acid), nasal spray (Nasacort, Nasacort Allergo), cream (Pevisone + Econazole). Structure and properties Triamcinolone acetonide (C24H31FO6, Mr = 434.5 g/mol) is a white crystalline powder that is … Triamcinolone Acetonide

Triamcinolone Acetonide Nasal Spray

Products Triamcinolone acetonide nasal sprays have been approved in many countries since 1996 and are commercially available as propellant-free metered-dose sprays (Nasacort, Nasacort Allergo, Suspension). Structure and properties Triamcinolone acetonide (C24H31FO6, Mr = 434.5 g/mol) is a white crystalline powder that is practically insoluble in water. It is a lipophilic and potent derivative of triamcinolone. … Triamcinolone Acetonide Nasal Spray

Volon A

Synonym Triamcinolone acetonideVolon® A is a drug belonging to the glucocorticoid group. Glucocorticoids have the property of counteracting inflammation and allergies and reducing the body’s immune response. Due to these three properties of Volon® A it can be used in a wide range of diseases. The application ranges from inflammatory skin diseases to rheumatic diseases … Volon A

Contraindications | Volon A

Contraindications Volon® A is not recommended in cases of immunodeficiency, as it additionally suppresses the immune system. Volon® A can also not be used in case of severe infections. In cases of damage to the gastrointestinal mucosa, severe osteoporosis and mental illness, the advantages and disadvantages of therapy with Volon® A must be weighed up. … Contraindications | Volon A

Mometasone

Products Mometasone furoate is commercially available as a cream, ointment, emulsion, and solution (Elocom, Monovo, Ovixan). It has been approved in many countries since 1989. This article refers to use on the skin. Nasal sprays are also available; see mometasone nasal spray. In 2020, a fixed combination with indacaterol was approved for asthma therapy (Atectura … Mometasone

Mometasone Inhalation

Products Mometasone powder inhaler was approved in many countries since 2005 (Asmanex Twisthaler). Mometasone furoate is also used to treat skin disorders and to treat disorders of the nasal mucosa; see Mometasone (dermal) and Mometasone nasal spray. Structure and properties Mometasone (C22H28Cl2O4, Mr = 427.4 g/mol) is present in the drug as mometasone furoate, a … Mometasone Inhalation