Candesartan

Products Candesartan is commercially available in tablet form (Atacand, Blopress, generics). It is also combined fixed with hydrochlorothiazide (Atacand plus, Blopress plus, generics). Candesartan has been approved in many countries since 1997. In 2020, a fixed combination with amlodipine was also released. Structure and Properties Candesartan (C24H20N6O3, Mr = 440.45 g/mol) is administered in the … Candesartan

Losartan

Products Losartan is commercially available in the form of film-coated tablets (Cosaar, generics). It has been approved in many countries since 1994 and was the first agent in the sartan group. Losartan is also combined with the diuretic hydrochlorothiazide (Cosaar Plus, generic). Structure and properties Losartan (C22H23ClN6O, Mr = 422.9 g/mol) is a biphenyl, imidazole, … Losartan

Ion Exchange Resins

Indications Hyperlipidemia Agents Colestyramine (Quantalan) Colestipol (Colestid) Sodium polystyrene sulfonate (Resonium A) for the treatment of hyperkalemia. Resina polystyrenolica anionica fortis (Ipocol).

Irbesartan

Products Irbesartan is commercially available in the form of film-coated tablets as a monopreparation (Aprovel, generic) and as a fixed combination with hydrochlorothiazide (Co-Aprovel). It has been approved in many countries since 1997. Generics entered the market in many countries in August 2012. Generic versions of the combination preprinted with hydrochlorothiazide went on sale in … Irbesartan

Red Foxglove

Products Preparations from the leaves of foxglove are rarely used medicinally today. Medicines containing the ingredient digitoxin are available in some countries. Digoxin, the pure substance extracted from foxglove, is commercially available in many countries in the form of tablets (Digoxin Sandoz). Stem plant Red foxglove, a member of the plantain family (Plantaginaceae), is native … Red Foxglove

Benazepril

Products Benazepril was commercially available as film-coated tablets (Cibacen, off label). It was also available as a fixed-dose combination with hydrochlorothiazide (Cibadrex, off label). Benazepril was approved in many countries beginning in 1990. Structure and properties Benazepril (C24H28N2O5, Mr = 424.5 g/mol) is present in drugs as benazepril hydrochloride, a white crystalline powder that is … Benazepril

Aliskiren

Products Aliskiren is commercially available in the form of film-coated tablets (Rasilez, Rasilez HCT + hydrochlorothiazide). It was approved in many countries, in the EU and in the United States in 2007 (Other brand name: Tekturna). Note: Other combination preparations, e.g., with amlodpine (Rasilamlo), are no longer available. Structure and properties Aliskiren (C30H53N3O6, Mr = … Aliskiren

Teriflunomide

Products Teriflunomide is commercially available in the form of film-coated tablets (Aubagio). It was approved in many countries in 2013. Teriflunomide can be taken perorally, unlike earlier MS medications, and does not need to be injected. Structure and properties Teriflunomide (C12H9F3N2O2, Mr = 270.2 g/mol) is the active metabolite of the prodrug leflunomide (Arava), which … Teriflunomide

Ringer Solutions

Products Ringer’s solutions are commercially available in many countries as infusion solutions from various manufacturers (e.g., Braun, Bichsel, Fresenius). Irrigation solutions for wound treatment are also available. The solutions are named after the English physician and pharmacologist Sidney Ringer (1835-1910), who discovered in 1883 that the addition of calcium to a saline solution maintains the … Ringer Solutions

Spironolactone

Products Spironolactone is commercially available in film-coated tablet form as a monopreparation (Aldactone) and in fixed combination with furosemide (Furospir). It was developed in the 1950s at G.D. Searle in Chicago and approved in 1959, and in many countries in 1961. Structure and properties Spironolactone (C24H32O4S, Mr = 416.6 g/mol) exists as a white to … Spironolactone

Potassium Citrate

Products Potassium citrate is commercially available in the form of modified-release tablets (Urocit). It has been approved in many countries since 2012. Potassium citrate is also found in salt mixes and foods. This article is related to the prevention of kidney stones. Structure and properties Potassium citrate (C6H5K3O7 – H2O, Mr = 324.4 g/mol) is … Potassium Citrate