Products Enalapril is commercially available in tablet form (Reniten, generics). It has been approved in many countries since 1984. The active ingredient is also combined fixed with hydrochlorothiazide. Structure and properties Enalapril (C20H28N2O5, 376.45 g/mol) is present in drugs as enalapril maleate, a white powder that is sparingly soluble in water. Enalapril is the prodrug … Enalapril: Drug Effects, Side Effects, Dosage and Uses
Products Perindopril is commercially available in the form of film-coated tablets and has been approved in many countries since 1989 (Coversum N, generic). It is also approved as a fixed combination with indapamide (Coversum N combi, generic) or amlodipine (Coveram, generic). Generic of the fixed combination with amlodipine was first registered in many countries in … Perindopril
Products Canrenone is commercially available as an injectable (Soldactone). It has been approved in many countries since 1975. Structure and properties Canrenone (C22H28O3, Mr = 340.5 g/mol) is an active metabolite of spironolactone (aldactone) and, unlike the latter, is soluble in water. Canrenone is present in drugs as potassium canrenoate, the potassium salt of canrenoic … Canrenon
Products Anidulafungin is commercially available as a powder for the preparation of an infusion solution (Ecalta, generics). It has been approved in many countries since 2009. Structure and properties Anidulafungin (C58H73N7O17, Mr = 1140.3 g/mol) is a cyclic lipopeptide. It is a semisynthetic echinocandin obtained from a fermentation product of . It exists as a … Anidulafungin
Products Sodium polystyrene sulfonate is commercially available in the form of a powder (Resonium A). It has been approved in many countries since 1968. Structure and properties Sodium polystyrene sulfonate is a polystyrene sulfonate resin in the sodium form. It has a defined exchange capacity for potassium ions per gram of dried substance. Sodium polystyrene … Sodium Polystyrene Sulfonate
Products Trimethoprim and sulfamethoxazole are commercially available in tablet and syrup form (Bactrim, generics). The drug has been approved in many countries since 1969. The Bactrim syrup is no longer available, but a generic is available (Nopil syrup). The fixed combination of the two active ingredients is also called cotrimoxazole. Structure and properties Trimethoprim (C14H18N4O3, … Trimethoprim and Sulfamethoxazole
Definition When two or more drugs are combined, they may affect each other. This is especially true with regard to their pharmacokinetics (ADME) and effects and adverse effects (pharmacodynamics). This phenomenon is called interaction and drug-drug interaction. Interactions are usually undesirable because they can lead to, for example, loss of efficacy, side effects, poisoning, hospitalization, … Interactions
Products Telmisartan is commercially available in tablet form (Micardis, Micardis Plus + hydrochlorothiazide, generics). It has been approved in many countries since 1998. Generics entered the market in December 2013. In 2010, a fixed combination with amlodipine was registered (Micardis Amlo). Kinzal is no longer marketed in many countries. Structure and properties Telmisartan (C33H30N4O2, Mr … Telmisartan
Products Cilazapril is commercially available in the form of film-coated tablets (Inhibace). Fixed combinations with hydrochlorothiazide are available (Inhibace plus). Cilazapril has been approved in many countries since 1990. Structure and properties Cilazapril (C22H31N3O5, Mr = 417.5 g/mol) exists as a white crystalline powder that is sparingly soluble in water. It is a prodrug that … Cilazapril
Products Drospirenone is commercially available as a fixed combination with ethinyl estradiol for contraception in the form of film-coated tablets (Yasmin, Yasminelle, YAZ, generics, auto-generics). Drospirenone is also used in combination with estradiol for hormone replacement therapy (Angeliq). Bayer’s originals Yasmin, Yasminelle and YAZ will go off the market in many countries in December 2021. … Drospirenone
Products Basiliximab is commercially available as an injectable (Simulect, Novartis). It has been approved in many countries, in the EU, and in the United States since 1998. Structure and properties Basiliximab is a chimeric monoclonal human murine IgG1κ antibody with a molecular mass of 144 kDa. It is produced by biotechnological methods. The drug name … Basiliximab
Products Diuretics are mainly administered in the form of tablets. In addition, injectables are also commercially available. Among the most commonly prescribed diuretics are loop diuretics (torasemide). Effects Diuretics (ATC C03) have diuretic and antihypertensive properties. Through various mechanisms, they cause increased excretion of water and electrolytes in the urine. They are active at the … Diuretics (Water Pills): Effects, Side Effects, Dosage and Uses
