Quinapril

Products Quinapril is commercially available in the form of film-coated tablets as a monopreparation (Accupro) and as a fixed combination with hydrochlorothiazide (Accuretic, Quiril comp). It has been approved in many countries since 1989. Generic versions are registered. Structure and properties Quinapril (C25H30N2O5, Mr = 438.5 g/mol) is present in drugs as quinapril hydrochloride, a … Quinapril

ACE Inhibitors List, Effects, Side Effects

Products Most ACE inhibitors are commercially available in the form of tablets and film-coated tablets. The first agent from this group to be approved was captopril, in many countries in 1980. ACE inhibitors are often combined with the thiazide diuretic hydrochlorothiazide (HCT) fix. Structure and properties ACE inhibitors are peptidomimetics derived from peptides found in … ACE Inhibitors List, Effects, Side Effects

Suxamethonium Chloride

Products Suxamethonium chloride is commercially available as a solution for injection (lysthenone, succinoline). It was introduced in the 1950s and has been approved in many countries since 1954. Suxamethonium chloride is also known as succinylcholine or succinylcholine chloride, especially in English. In jargon, it is also called Suxi or Sux. Structure and properties Suxamethonium chloride … Suxamethonium Chloride

Patiromer

Products Patiromer was approved in the United States in 2015 and in many countries and the EU in 2017 as a powder for oral suspension (Veltassa). Structure and properties Patiromer is a nonabsorbable cation exchange polymer containing a calcium–sorbitol complex as a counterion. It exists as a white powder that is virtually insoluble in water. … Patiromer

Sartans

Products Most sartans are commercially available as tablets or film-coated tablets. Losartan was the first agent approved in many countries in 1994 (Cosaar, USA: 1995, Cozaar). Sartans are often combined with hydrochlorothiazide fix. The name of the drug group is derived from the suffix -sartan of the active ingredients. The drugs are also called angiotensin … Sartans

Potassium Health Benefits

Products Potassium is commercially available, among other things, in the form of effervescent tablets (so-called effervettes), as sustained-release dragées and sustained-release tablets (e.g., Kalium Hausmann, KCl-retard, Plus Kalium). It is also contained in sports drinks such as Isostar or Sponser. The dose is usually expressed in millimoles (mmol) or milliequivalents (mEq): 1 mmol = 39.1 … Potassium Health Benefits

Beta2-Sympathomimetics

Products Beta2-sympathomimetics are usually commercially available as inhalation preparations (powders, solutions) administered with an inhaler, for example, metered-dose inhaler, diskus, Respimat, Breezhaler, or Ellipta. There are few drugs on the market that can be given perorally. Structure and properties Beta2-sympathomimetics are structurally related to the natural ligands epinephrine and norepinephrine. They may exist as racemates … Beta2-Sympathomimetics

Tacrolimus (Protopic, Prograf): Drug Effects, Side Effects, Dosage and Uses

Products Tacrolimus is commercially available in the form of capsules, sustained-release capsules, sustained-release tablets, as a concentrated solution for infusion, as granules, and as an ointment (Prograf, generic, Advagraf, Protopic, generic, Modigraf). It has been approved in many countries since 1996. This article refers to oral use; see also Topical Tacrolimus (Protopic Ointment). Structure and … Tacrolimus (Protopic, Prograf): Drug Effects, Side Effects, Dosage and Uses

Olmesartan

Products Olmesartan is commercially available in the form of film-coated tablets (Olmetec, Votum, fixed combinations with amlodipine and hydrochlorothiazide). It has been approved in many countries since 2005. Generics were registered in 2016 and went on sale in 2017. Structure and properties Olmesartan is present in drugs as olmesartan medoxomil (C29H30N6O6, Mr = 558.6 g/mol), … Olmesartan

Lisinopril: Drug Effects, Side Effects, Dosage and Uses

Products Lisinopril is commercially available in tablet form as a monopreparation (Zestril, generic) and as a fixed combination with hydrochlorothiazide (Zestoretic, generic). It has been approved in many countries since 1989. Structure and properties Lisinopril (C21H31N3O5, Mr = 405.49 g/mol) is present in drugs as lisinopril dihydrate, a white crystalline powder that is soluble in … Lisinopril: Drug Effects, Side Effects, Dosage and Uses

Valsartan

Products Valsartan is commercially available in the form of film-coated tablets and has been approved since 1996 (Diovan, generic). The active ingredient is also combined fixed with other agents: Hydrochlorothiazide (co-Diovan, Exforge HCT with amlodipine, generics). Amlodipine (Exforge, generic). Sacubitril (Entresto) Valsartan scandal: in July 2018, numerous generic drugs had to be recalled from the … Valsartan