Products Liraglutide was approved in many countries in 2009 as a solution for injection in a prefilled pen (Victoza). In 2014, a fixed-dose combination with insulin degludec was released (Xultophy); see IDegLira. In 2016, Saxenda was registered for the treatment of overweight and obesity. Its related successor, semaglutide, unlike liraglutide, only needs to be injected … Liraglutide
Symptoms The possible symptoms of a transient ischemic attack (TIA) include: Visual disturbances, temporary blindness Difficulty swallowing Sensory disturbances such as numbness or formication. Speech disorders Coordination disorders, loss of balance, paralysis. Behavioral disturbances, fatigue, drowsiness, agitation, psychosis, memory impairment. The symptoms occur suddenly, are transient and last only briefly, during a maximum of one … Transient Ischemic Attack
In anterior pituitary insufficiency, there is a partial or complete failure of anterior pituitary hormones. These hormones include control hormones that act on other endocrine glands and effector hormones that have a direct effect on organs. The failed hormones can be therapeutically substituted. What is anterior pituitary insufficiency? The anterior pituitary gland forms the largest … Anterior Pituitary Insufficiency: Causes, Symptoms & Treatment
Stem plant Fabaceae, true geissraute. Medicinal drug Galegae herba – goat’s rue herb. Ingredients Guanidine derivatives: galegine (cf. metformin). Flavonoids Tannins Effects Blood sugar lowering Indications for use In folk medicine as an antidiabetic. Commission E gives a negative evaluation of its use. Dosage The use is not recommended. Adverse effects Hypoglycemia, possibly poisoning.
Background Hypoglycemia (low blood sugar) often occurs as an adverse effect of antidiabetic drugs. It manifests as activation of the sympathetic nervous system with sweating, palpitations, nausea, tremors, and even unconsciousness and coma. At the first signs of hypoglycemia, the patient should immediately consume 24 to 36 g of glucose (corresponding to 2-3 bread units; … Liquid Dextrose
Products Empagliflozin is commercially available in the form of film-coated tablets. It was approved in the EU, the United States, and many countries in 2014 (Jardiance). Empagliflozin is also combined fixed with metformin (Jardiance Met) as well as with linagliptin (Glyxambi). Trijardy XR is a fixed combination of empagliflozin, linagliptin, and metformin. Structure and properties … Empagliflozin
Products Metformin is commercially available in many countries in the form of film-coated tablets and has been available since 1960. In addition to the original Glucophage, numerous generics are available today. Metformin is often combined with various other antidiabetic drugs fix. It has been used medically since 1957. Other antidiabetic biguanides such as phenformin and … Metformin: Drug Effects, Side Effects, Dosage and Uses
Products Perindopril is commercially available in the form of film-coated tablets and has been approved in many countries since 1989 (Coversum N, generic). It is also approved as a fixed combination with indapamide (Coversum N combi, generic) or amlodipine (Coveram, generic). Generic of the fixed combination with amlodipine was first registered in many countries in … Perindopril
Products Glibenclamide is commercially available in tablet form (Daonil, generics). It has been approved in many countries since 1970 and is also used in fixed combination with metformin (Glucovance). Structure and properties Glibenclamide (C23H28ClN3O5S, Mr = 494.0 g/mol) is a sulfonylurea. It exists as a white crystalline powder that is practically insoluble in water. Effects … Glibenclamide
Products Glibornuride was commercially available in tablet form (Glutril, originally Roche, later MEDA Pharma). It was approved in many countries since 1971. It was discontinued in 2019. Structure and properties Glibornuride (C18H26N2O4S, Mr = 366.48 g/mol) is a sulfonylurea. Effects Glibornuride (ATC A10BB04) has antihyperglycemic and antidiabetic properties. The effects are due to the promotion … Glibornuride
Products Gliclazide has been commercially available in sustained-release tablet form and approved in many countries since 1978. The sustained-release dosage forms entered the market in 2001. In addition to the original Diamicron MR, sustained-release generics have been available since 2008. Sales of the non-retarded Diamicron 80 mg were discontinued in 2012. Structure and properties Gliclazide … Gliclazide
Products Glimepiride is commercially available in tablet form (Amaryl, generic). It has been approved in many countries since 1995. Structure and properties Glimepiride (C24H34N4O5S, Mr = 490.62 g/mol) exists as a white to yellowish-white, crystalline and odorless powder that is practically insoluble in water. It belongs structurally to the sulfonylureas. Effects Glimepiride (ATC A10BB12) has … Glimepiride
