Products Oclacitinib is commercially available in the form of film-coated tablets for dogs (Apoquel). It has been approved in many countries since 2014. Structure and properties Oclacitinib (C15H23N5O2S, Mr = 337.4 g/mol) is present in the drug as oclacitinib maleate. Effects Oclacitinib (ATCvet QD11AH90) has anti-inflammatory, antiallergic, and antipruritic properties. The effects are due to … Oclacitinib
Products Sulpiride is commercially available in the form of capsules and tablets (Dogmatil). It has been approved in many countries since 1976. Structure and properties Sulpiride (C15H23N3O4S, Mr = 341.4 g/mol) is a racemate. It exists as a white crystalline powder that is practically insoluble in water. It belongs to the substituted benzamides. Effects Sulpiride … Sulpiride (Dogmatil): Drug Effects, Side Effects, Dosage and Uses
Products Sunitinib is commercially available in capsule form (Sutent). It has been approved in many countries since 2006. Structure and properties Sunitinib (C22H27FN4O2, Mr = 398.5 g/mol) is present in the drug as sunitinibmalate, a yellow to orange powder that is soluble in water. It is an indolin-2-one and pyrrole derivative. It has an active … Sunitinib
Products The fixed combination of netupitant and palonosetron has been approved in capsule form (Akynzeo). The drug was released in many countries in 2015. Structure and properties Netupitant (C30H32F6N4O, Mr = 578.6 g/mol) is a fluorinated piperazine and pyrimidine derivative. Palonosetron (C19H24N2O, Mr = 296.4 g/mol) is present in drugs as palonosetron hydrochloride, a white … Netupitant, Palonosetron
Products Lymecycline is commercially available in the form of capsules (Tetralysal). It was approved in many countries in 2005. Structure and properties Lymecycline (C29H38N4O10, Mr = 602.6 g/mol) is a water-soluble prodrug of the antibiotic tetracycline with the amino acid lysine. Lymecycline is better absorbed than tetracycline. Effects Lymecycline (ATC J01AA04) has bacteriostatic properties against … Lymecycline
Products Ezetimibe is commercially available in tablet form, as a monopreparation (Ezetrol, generic), and as a fixed combination with simvastatin (Inegy, generic) and with atorvastatin (Atozet). Also released is a combination with rosuvastatin. Ezetimibe was approved in many countries and in the United States in 2002. Generic and auto-generics entered the market in November 2017. … Ezetimibe
Products Abacavir is commercially available as film-coated tablets and as an oral solution (Ziagen, combination products). It has been approved in many countries since 1999. Generic versions are approved. Structure and properties Abacavir (C14H18N6O, Mr = 286.3 g/mol) is present in drugs, among other forms, as abacavir sulfate, a white crystalline powder that is soluble … Abacavir
Products Abemaciclib was approved in the form of film-coated tablets in the United States in 2017, in the EU in 2018, and in many countries in 2019 (Verzenios). Structure and properties Abemaciclib (C27H32F2N8, Mr = 506.6 g/mol) exists as a white to yellow powder. Effects Abemaciclib (ATC L01XE50) has antitumor and antiproliferative properties. The effects … Abemaciclib
Products Solifenacin is commercially available in the form of film-coated tablets (Vesicare, generics). It has been approved in many countries since 2006. Structure and properties Solifenacin (C23H26N2O2, Mr = 362.5 g/mol) is a tertiary amine and a phenylquinoline derivative that has structural similarities to atropine. It is present in drugs as (1)-(3)-solifenacin succinate, a white … Solifenacin
Products Solriamfetol was approved in the United States in tablet form in 2019 (Sunosi). Structure and properties Solriamfetol (C10H14N2O2, Mr = 194.2 g/mol) is present in the drug as -solriamfetol hydrochloride, a white substance that is highly soluble in water. Solriamfetol is a carbamate and structurally related to amphetamines but pharmacologically distinct from them. Effects … Solriamfetol
Products Saxagliptin is commercially available in the form of film-coated tablets (Onglyza). It was approved in many countries after sitagliptin (Januvia) and vildagliptin (Galvus) as the 3rd active ingredient from the gliptins group in February 2010. Since 2012, two additional combination products with metformin have been registered (Duoglyze, Kombiglyze XR). Kombiglyze XR entered the market … Saxagliptin
Products Cariprazine was approved in the United States in 2015 and in many countries and the EU in 2018 in capsule form (Reagila, some countries: Vraylar). Structure and properties Cariprazine (C21H32Cl2N4O, Mr = 427.4 g/mol) is a piperazine and dimethylurea derivative. It is present in the drug as cariprazine hydrochloride, a white powder. Active metabolites … Cariprazine
