Products Zolmitriptan is commercially available as film-coated tablets, meltable tablets, and as a nasal spray (Zomig, generics). It has been approved in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Zolmitriptan (C16H21N3O2, Mr = 287.4 g/mol) is an indole and oxazolidinone derivative structurally related to serotonin. It exists as … Zolmitriptan
Products Rizatriptan is commercially available in tablet and lingual (melting) tablet form (Maxalt, generics). It has been approved in many countries since 2000. Generic versions went on sale in 2015. Structure and properties Ritatriptan (C15H19N5, Mr = 269.3 g/mol) is present in drugs as rizatriptan benzoate, a white crystalline powder that is soluble in water. … Rizatriptan
Products Ondansetron is commercially available in the form of film-coated tablets, meltable tablets (lingual tablets), as a syrup, and as an infusion/injection preparation. In addition to the original Zofran, generic versions are also available. Ondansetron was introduced in 1991 as the first active ingredient from the group of 5-HT3 receptor antagonists was approved. Structure and … Ondansetron
Products Panobinostat was approved in many countries in 2015 in capsule form (Farydak). Structure and properties Panobinostat (C21H23N3O2, Mr = 349.4 g/mol) is present in the drug as panobinostat lactate, a white to slightly yellow or brownish powder that is sparingly soluble in water. It is an indole, a hydroxamic acid, and a propenamide derivative. … Panobinostat
Products Telmisartan is commercially available in tablet form (Micardis, Micardis Plus + hydrochlorothiazide, generics). It has been approved in many countries since 1998. Generics entered the market in December 2013. In 2010, a fixed combination with amlodipine was registered (Micardis Amlo). Kinzal is no longer marketed in many countries. Structure and properties Telmisartan (C33H30N4O2, Mr … Telmisartan
Products Tegaserod (Zelmac, Zelnorm, tablets) was approved in many countries in 2001. After showing an increased risk of ischemic cardiovascular events such as heart attack and stroke, Novartis withdrew the drug from the market in 2007 on orders from Swissmedic. Structure and properties Tegaserod (C16H23N5O, Mr = 301.4 g/mol) exists as tegaserodmaleate, a white crystalline … Tegaserod
Products Etodolac is commercially available as film-coated tablets and sustained-release film-coated tablets (Lodine, Lodine retard). It has been approved in many countries since 1987. Structure and properties Etodolac (C17H21NO3, Mr = 287.4 g/mol) is a racemate. The -enantiomer is pharmacologically more active. Etodolac exists as a white crystalline powder that is practically insoluble in water. … Etodolac
Products Tropisetron was approved in many countries starting in 1992 as a solution for injection and in capsule form (Navoban). It was withdrawn from the market in 2013. Structure and properties Tropisetron (C17H20N2O2, Mr = 284.4 g/mol) is an indole and tropane derivative. It exists as a white powder that is soluble in water. Effects … Tropisetron
Products In many countries, tryptophan is commercially available as a dietary supplement, for example, in the form of capsules. Structure and properties L-tryptophan (C11H12N2O2, Mr = 204.2 g/mol) is an essential aromatic amino acid derived from indole. It exists as a white, crystalline or amorphous powder that is sparingly soluble in water. Effects Tryptophan (ATC … Tryptophan
Products Naratriptan is commercially available in the form of film-coated tablets (Naramig). It has been approved in many countries since 1997. Structure and properties Naratriptan (C17H25N3O2S, Mr = 335.5 g/mol) is structurally related to serotonin and is an indole and piperidine derivative. It is present in drugs as naratriptan hydrochloride, a white to slightly yellowish … Naratriptan: Drug Effects, Side Effects, Dosage and Uses
