Products Indometacin is commercially available as sustained-release capsules, indometacin eye drops (Indophtal), and solution for application (Elmetacin). This article refers to oral administration. The sustained-release capsules have been on the market in many countries since 1995 (Indocid, generic). Structure and properties Indomethacin (C19H16ClNO4, Mr = 357.8 g/mol) is an indoleacetic acid derivative. It exists as … Indometacin
Products Indometacin has been approved in many countries since 1999 in the form of eye drops (Indophtal, Indophtal UD). Structure and properties Indomethacin (C19H16ClNO4, Mr = 357.8 g/mol) is an indoleacetic acid derivative. It exists as a white to yellow crystalline powder that is practically insoluble in water. Effects Indomethacin (ATC S01BC01) has analgesic and … Indomethacin Eye Drops
Definition Pharmaceutical agents are excreted primarily in the urine and, via the liver, in the bile in the stool. When excreted via the bile, they re-enter the small intestine, where they may be reabsorbed. They are transported back to the liver via the portal vein. This repetitive process is called the enterohepatic circulation. It prolongs … Enterohepatic Circulation
The term paroxysmal hemicrania describes a specific form of headache disorder. It is characterized by seizure-like, hemiparesis, very severe attacks of pain accompanied by redness on the affected side of the face. The duration of the attacks is from a few minutes to about 45 minutes in rare cases. What is paroxysmal hemicrania? Infographic on … Paroxysmal Hemicrania: Causes, Symptoms & Treatment
Symptoms Alzheimer’s disease manifests itself in a continuously progressive loss of memory and mental and cognitive abilities. Possible symptoms of the disease include: Disorders and loss of memory. Initially, mainly short-term memory is affected (learning new things), later long-term memory is also affected. Forgetfulness, confusion Disorientation Speech, perception and thinking disorders, motor disorders. Personality change, … Alzheimer’s
Products Ketorolac commercially available in the form of film-coated tablets, as a solution for injection (Tora-Dol), and as eye drops (Acular, generic). It has been approved in many countries since 1992. Structure and properties Ketorolac (C15H13NO3, Mr = 255.7 g/mol) is present in drugs in the form of the salt ketorolactrometamol (= ketorolactromethamine), see also … Ketorolac
Products Trimethoprim and sulfamethoxazole are commercially available in tablet and syrup form (Bactrim, generics). The drug has been approved in many countries since 1969. The Bactrim syrup is no longer available, but a generic is available (Nopil syrup). The fixed combination of the two active ingredients is also called cotrimoxazole. Structure and properties Trimethoprim (C14H18N4O3, … Trimethoprim and Sulfamethoxazole
Indications Inhibition of labor during pregnancy to prevent preterm delivery Active ingredients Minerals: Magnesium (e.g. magnesium diasporal). Calcium channel blockers: Nifedipine (Adalat, generic, off-label). Progestins: Progesterone (Utrogestan) Probiotics: Lactobacilli (vaginal suppositories to prevent infections). Oxytocin antagonists: Atosiban (Tractocile). Sympathomimetics: Hexoprenaline (Gynipral) Fenoterol (no indication in many countries). Salbutamol (Ventolin, no indication in many countries). Other … Labor Inhibitors
Symptoms Snow blindness occurs with a delay within approximately 3-12 hours after exposure to UV radiation, often in the afternoon, evening, or night. It manifests itself in the following symptoms: Unbearable pain in both eyes Foreign body sensation, “sand in the eyes” Trickling of tears Conjunctivitis and redness, conjunctival swelling. Corneal inflammation Eyelid spasm, i.e. … Snowblind
Products Benazepril was commercially available as film-coated tablets (Cibacen, off label). It was also available as a fixed-dose combination with hydrochlorothiazide (Cibadrex, off label). Benazepril was approved in many countries beginning in 1990. Structure and properties Benazepril (C24H28N2O5, Mr = 424.5 g/mol) is present in drugs as benazepril hydrochloride, a white crystalline powder that is … Benazepril
Products Glucagon is commercially available as an injectable (GlucaGen). It has been approved in many countries since 1965. It is available to patients as a powder and solvent for preparing a solution for injection in a prefilled syringe. The drug is stored in a cool place in the pharmacy until dispensed. Patients can store it … Glucagon (Syringe)
Products Glucagon nasal applicator was approved in the US and EU in 2019 and in many countries in 2020 (Baqsimi, single dose). Glucagon is present in the drug product as a powder for nasal administration. The applicator is stored at room temperature not above 30°C. Structure and properties Glucagon (C153H225N43O49S, Mr = 3483 g/mol) is … Glucagon Nasal Spray
