Symptoms The infection is usually asymptomatic. Transient pulmonary symptoms such as cough, dyspnea, asthma-like symptoms, Löffler syndrome with eosinophilic pulmonary infiltrates occur. The pulmonary symptoms are the result of the larvae migrating into the lungs. Other symptoms include fever, abdominal pain, nausea, and vomiting. Worm eggs are first found in the stool 7-9 weeks after … Roundworm (Ascaris Lumbricoides)
Products Ocriplasmin is commercially available as an injectable (Jetrea). It has been approved in many countries since 2014. Structure and properties Ocriplasmin is a recombinant and truncated derivative of the human proteolytic enzyme plasmin with a molecular weight of 27.2 kDa. It is produced by biotechnological methods. Effects Ocriplasmin (ATC S01XA22) has proteolytic properties on … Ocriplasmin
Products Revefenacin was approved in the United States in 2018 as a monodose inhalation solution (Yupelri). The active ingredient belongs to the LAMA group. Structure and properties Revefenacin (C35H43N5O4, Mr = 597.8 g/mol) exists as a white crystalline powder and is sparingly soluble in water. It has an active metabolite formed by hydrolysis. Effects Revefenacin … Revefenacin
Structure of the skin The skin (cutis), with an area of about 2 m2 and accounting for 15% of body weight, it is one of the largest organs in humans. It consists of the epidermis (upper skin) and the dermis (leather skin) underneath. The outermost layer, the epidermis, is a keratinized, multilayered squamous epithelium without … Skin
Products Heberprot-P is a Cuban drug developed in Havana am and has been on the market since 2007. It is now available as an injectable in numerous countries. It is not currently registered in many countries. Structure and properties Heberprot-P contains recombinant human epidermal growth factor (rhEGF), a comparatively small protein with 53 amino acids … Siphonprot-P
Products Abatacept is commercially available as an injection and infusion preparation (Orencia). It was approved in the United States in 2005 and in the EU and many countries in 2007. Structure and properties Abatacept is a recombinant fusion protein with the following components: Extracellular domain of CTLA-4 (cytotoxic T-lymphocyte-associated protein 4). Modified Fc domain of … Abatacept
Products Evolocumab was approved in the EU and US in 2015 and in many countries in 2016 in the form of a solution for injection (Repatha). Structure and properties Evolocumab is a human IgG2 monoclonal antibody with a molecular mass of 141.8 kDa. It is produced by biotechnological methods. Effects Evolocumab (ATC C10AX13) has lipid-lowering … Evolocumab
Products Abemaciclib was approved in the form of film-coated tablets in the United States in 2017, in the EU in 2018, and in many countries in 2019 (Verzenios). Structure and properties Abemaciclib (C27H32F2N8, Mr = 506.6 g/mol) exists as a white to yellow powder. Effects Abemaciclib (ATC L01XE50) has antitumor and antiproliferative properties. The effects … Abemaciclib
In medicine, a burst belly is the bursting of the surgical wound after open abdominal surgery. Potential causes of abdominal bursting include poor wound healing, obesity, and physical stress. What is a burst belly? Abdominal bursting is a complication following open laparotomy. A laparotomy is a surgical procedure for which the abdominal wall is opened … Belly: Causes, Symptoms & Treatment
Products Ofatumumab was approved in 2009 as a concentrate for the preparation of an infusion solution for leukemia treatment (Arzerra). In 2020, a solution for injection was approved in the United States for MS treatment (Kesimpta). Structure and properties Ofatumumab is a human IgG1 monoclonal antibody produced by biotechnological methods. It has a molecular mass … Ofatumumab
Products Preparations from the balloon vine are commercially available in the form of ointments, creams, lotions, as sprays, drops and globules, among others. This article refers to the external use as Cardiospermum cream or ointment (e.g., Omida Cardiospermum, Halicar). The ointment has been approved in many countries since 1989. Stem plant The balloon vine or … Cardiospermum Effects and Side Effects
Products TNF-α inhibitors are commercially available as injectable and infusion preparations. Infliximab (Remicade) was the first agent from this group to be approved in 1998, and in many countries in 1999. Biosimilars of some representatives are now available. Others will follow in the next few years. This article refers to biologics. Small molecules can also … TNF-Α Inhibitors
