Nabilon

Products Nabilone is commercially available in the United States, the United Kingdom, and Germany, for example, in the form of capsules (Cesamet, Canemes). It is a narcotic drug. In many countries, the drug is not registered. The active ingredient was developed in the 1970s. Structure and properties Nabilone (C24H36O3, Mr = 372.5 g/mol) is a … Nabilon

Bismuth, Metronidazole, Tetracycline

Products The fixed combination Pylera with the active ingredients bismuth, metronidazole, and tetracycline was approved in many countries in 2017 in the form of hard capsules. In some countries, it was available much earlier, for example, in the United States since 2006. This treatment is the so-called bismuth quadruple therapy (“BMTO”), which was developed by … Bismuth, Metronidazole, Tetracycline

Oclacitinib

Products Oclacitinib is commercially available in the form of film-coated tablets for dogs (Apoquel). It has been approved in many countries since 2014. Structure and properties Oclacitinib (C15H23N5O2S, Mr = 337.4 g/mol) is present in the drug as oclacitinib maleate. Effects Oclacitinib (ATCvet QD11AH90) has anti-inflammatory, antiallergic, and antipruritic properties. The effects are due to … Oclacitinib

Solriamfetol

Products Solriamfetol was approved in the United States in tablet form in 2019 (Sunosi). Structure and properties Solriamfetol (C10H14N2O2, Mr = 194.2 g/mol) is present in the drug as -solriamfetol hydrochloride, a white substance that is highly soluble in water. Solriamfetol is a carbamate and structurally related to amphetamines but pharmacologically distinct from them. Effects … Solriamfetol

Hydralazine: Effects, Uses & Risks

Hydralazine is a drug that has a vasodilator effect. It is used to treat heart failure as well as hypertension during pregnancy. What is hydralazine? Hydralazine belongs to the group of vasodilators. These are vasodilating agents that are used to lower high blood pressure. In Europe, however, the related dihydralazine is more commonly used. The … Hydralazine: Effects, Uses & Risks

Lisdexamphetamine

Products Lisdexamphetamine (LDX) was approved in many countries in March 2014 in capsule form (Elvanse). It has been available in the United States since 2007 (Vyvanse). The dosage form is non-retarded, unlike other ADHD medications. Continuous release is achieved with the conversion of the prodrug. Lisdexamphetamine is legally classified as a narcotic and therefore requires … Lisdexamphetamine

Hydromorphone

Products Hydromorphone is commercially available as sustained-release tablets, sustained-release capsules, capsules, solution for injection, solution for infusion, and drops (e.g., Palladon, Jurnista, Hydromorphoni HCl Streuli). It has been approved in many countries since 1996. Structure and properties Hydromorphone (C17H19NO3, Mr = 285.3 g/mol) is a semisynthetic, hydrogenated and oxidized morphine derivative. It is present in … Hydromorphone

Pembrolizumab

Products Pembrolizumab was approved as an infusion product in the United States in 2014 and in the EU and many countries in 2015 (Keytruda). Structure and properties Pembrolizumab is a humanized monoclonal antibody. It is an IgG4-κ immunoglobulin with a molecular weight of approximately 149 kDa. Effects Pembrolizumab (ATC L01XC18) has antitumor and immunomodulatory properties. … Pembrolizumab

Cannabidiol Hemp

Products Hemp with a high content of cannabidiol and a low total content of tetrahydrocannabinol (less than 1%) can be legally sold in many countries since 2016 and is available from specialized suppliers and web stores. Cannabidiol hemp is approved as a tobacco substitute product and not yet as a medicine. Neither cannabidiol nor cannabidiol … Cannabidiol Hemp

Cannabis Mouth Spray

Products The cannabis oral spray Sativex was approved in many countries in 2013. It is subject to narcotics legislation and requires an enhanced prescription. In Germany, Sativex has been available since 2011. Structure and properties The oral spray contains a thick extract of the hemp plant L., which is extracted from the leaves and flowers … Cannabis Mouth Spray

Appendicitis: Inflammation of the Appendix

Symptoms Appendicitis manifests as pain in the lower abdomen, which often begins in the area of the belly button, worsens, and moves to the lower right side of the abdomen within 24 hours. The pain increases with movement and with coughing. Possible accompanying symptoms include digestive disturbances such as nausea, vomiting, lack of appetite, bloating, … Appendicitis: Inflammation of the Appendix