Products Ceritinib is commercially available in capsule form (Zykadia). It was approved in the United States in 2014 and in the EU and many countries in 2015. In 2020, film-coated tablets were registered. Structure and properties Ceritinib (C28H36N5O3ClS, Mr = 558.14 g/mol) exists as a white to slightly yellow or slightly brown powder. Effects Ceritinib … Ceritinib
Symptoms The possible signs and symptoms of chronic myeloid leukemia include: Fatigue Feeling sick Bleeding tendency Susceptibility to infectious diseases Lack of appetite, digestive problems, weight loss. Fever Night sweats Enlargement of the spleen and liver, pain. Disorders of hematopoiesis, bone marrow changes Pale skin In the bone marrow and blood, a strong proliferation and … Chronic Myeloid Leukemia
Products Raltitrexed is commercially available as a powder for the preparation of an infusion solution (Tomudex). It was approved in many countries in 1998. Structure and properties Raltitrexed (C21H22N4O6S, Mr = 458.5 g/mol) is an analog of folic acid. Effects Raltitrexed (ATC L01BA03) has cytotoxic properties. The effects are due to selective inhibition of the … Raltitrexed
Products Dexamphetamine was reapproved in many countries in 2020 in tablet form (Attentin). Dexamine tablets (5 mg, Streuli) are no longer available. Also available is the prodrug lisdexamphetamine (Elvanse). Drugs containing dexamphetamine are also prepared as an extemporaneous prescription in a pharmacy or ordered by pharmacies from specialized service providers. Dexamphetamine is a narcotic and … Dexamphetamine
Products Selamectin is commercially available as a solution (Stronghold). It has been approved in many countries since 2000. Structure and properties Selamectin (C43H63NO11, Mr = 769.96 g/mol) is a semisynthetic derivative of avermectin. It is derived from doramectin. Effects Selamectin (ATCvet QP54AA05) has antiparasitic properties with a broad spectrum of activity. It kills eggs, larvae, … Selamectin
Products Ibrutinib is commercially available in capsule form (Imbruvica). It has been approved in many countries since 2014. Film-coated tablets were registered in 2019. Structure and properties Ibrutinib (C25H24N6O2, Mr = 440.5 g/mol) exists as a white substance that is practically insoluble in water. Effects Ibrutinib (ATC L01XE27) is a noncompetitive (irreversible) inhibitor of Bruton’s … Ibrutinib
Products Robenacoxib is commercially available in tablet form and as a solution for injection for dogs and cats (Onsior). It has been approved in many countries since 2009. Structure and properties Robenacoxib (C16H13F4NO2, Mr = 327.3 g/mol) is structurally related to diclofenac. Effects Robenacoxib (ATCvet QM01AH91) has analgesic and anti-inflammatory properties. The effects are due … Robenacoxib
Symptoms Malaria (Italian, “bad air”) manifests itself in the following symptoms, which usually appear a few weeks after transmission. The incubation period ranges from a few days to several years: High fever, sometimes with rhythmic attacks of fever, every second or third day. However, the fever may also occur irregularly. Chills, profuse sweating. Headache, muscle … Malaria Causes and Treatment
