pepsin

Hydrotalcite

Products Hydrotalcite was approved in many countries since 1992 and was commercially available as a suspension (Rennie Gel Hydrotalcite, off label). In Germany, it is also available as chewable tablets (Talcid, generic). Structure and properties Hydrotalcite (Al2Mg6(OH)16CO3 – 4H2O, Mr = 531.9 g/mol) is a magnesium aluminum hydroxide carbonate hydrate with a layered lattice structure. … Hydrotalcite

Magaldrat

Products Magaldrate is commercially available in tablet form and as an oral gel (Riopan, Riopan forte). It has been approved in many countries since 1985. Structure and properties Magaldrate is composed of aluminum and magnesium hydroxides and sulfates. The composition is approximately equivalent to the formula Al5Mg10(OH)31(SO4)2 – x H2O. Magaldrate exists as a white … Magaldrat

Roxatidine

Products No finished drug products containing roxatidine are commercially available in many countries. Structure and properties Roxatidine (C17H26N2O3, Mr = 306.4 g/mol) is present in the drug as roxatidine acetate, a prodrug that is metabolized in the body to the active drug. Effects Roxatidine (ATC A02BA06) inhibits the secretion of gastric acid and pepsin in … Roxatidine

Pepsin

Structure and properties Pepsin exists as a white to pale yellow, hygroscopic, crystalline or amorphous powder that is soluble in water. It is obtained from the gastric mucosa of pigs, cattle or sheep. Pepsin contains proteinases of the stomach that are active in an acidic environment (pH of 1 to 5). Effects Pepsin (ATC A09AA03) … Pepsin

Famotidine

Products Famotidine is not commercially available in many countries. In Germany and other countries, it is available in the form of film-coated tablets. Structure and properties Famotidine (C8H15N7O2S3, Mr = 337.4 g/mol) exists as a white to yellowish-white crystalline powder or as crystals and is very sparingly soluble in water. It is a thiazole derivative … Famotidine

Sucralfate

Products Sucralfate was commercially available in many countries since the year 1985 in the form of tablets, as a suspension, and as granules (Ulcogant). As of 2016, it is no longer available in many countries. It can be imported from abroad or replaced by other drugs. Structure and properties Sucralfate is a basic aluminum sucrose … Sucralfate

Ranitidine: Drug Effects, Side Effects, Dosage and Uses

Products Ranitidine was commercially available in the form of film-coated tablets, effervescent tablets, and as a solution for injection and had been approved since 1981 (Zantic, generic). Currently, drugs containing ranitidine are no longer available in many countries. Starting in 1996, tablets for self-medication with 75 mg were released. However, they are now also no … Ranitidine: Drug Effects, Side Effects, Dosage and Uses

H2 Receptor Antagonists

Products H2 receptor antagonists were commercially available in many countries in tablet, effervescent tablet, and solution for injection forms, among others. Currently, no more drugs are available. Due to proton pump inhibitors (PPI), H2 antagonists have become less important. The first active ingredient, cimetidine (Tagamet), was developed in the 1960s and 70s under the leadership … H2 Receptor Antagonists

Spasmo-Canulase

Products Spasmo-Canulase Bitabs (originally Wander, then Sandoz, Novartis, GSK) went on sale in many countries in 1964. In 2017, distribution was discontinued for production reasons. Procurement of the seven active ingredients apparently became increasingly difficult. Ingredients In the fast-dissolving shell of the tablets: Metixene (anticholinergic). Pepsin (digestive enzyme) Dimethicone (defoamer) Glutamic acid hydrochloride (acid) In … Spasmo-Canulase

Digestive Enzymes

Products Digestive enzymes are commercially available as drugs and dietary supplements, including tablets and capsules. Unlike other therapeutic proteins, they can be ingested and do not need to be injected. They can usually be stored at room temperature. Structure and properties Digestive enzymes are proteins produced by living organisms. They are obtained on the one … Digestive Enzymes

Lafutidin

Products No finished drug products containing lafutidine are commercially available in many countries. Structure and properties Lafutidine (C22H29N3O4S, Mr = 431.5 g/mol) Effects Lafutidine (ATC A02BA08) inhibits gastric acid and pepsin secretion in the stomach. Effects are due to antagonism at histamine H2 receptors. Indications For the treatment of gastric acid-associated disorders (eg, gastric distention, … Lafutidin