Products Minoxidil is commercially available as a solution and in some countries also as a foam (Regaine, generics, USA: Rogaine). It has been approved in many countries since 1987. The brand name plays on the English verb , which translates as to recover or get back. This article refers to external use. Tablets also exist … Minoxidil
Products Tiagabine was commercially available in the form of film-coated tablets (gabitril). It was approved in many countries in 1996 and went off the market in June 2012. Structure and properties Tiagabine (C20H25NO2S2, Mr = 375.5 g/mol) is a piperidine and thiophene derivative. It exists as a white crystalline powder that is sparingly soluble in … Tiagabine
Products Niraparib was approved in the US and EU in 2017 and in many countries in 2018 in hard capsule form (Zejula). Structure and properties Niraparib (C19H20N4O, Mr = 320.4 g/mol) is present in the drug as niraparibtosilate monohydrate. It is a piperidine, indazole, and carboxamide derivative. Effects Niraparib (ATC L01XX54) has antitumor and cytotoxic … Niraparib
Products Mizolastine was commercially available in tablet form (Mizollen, 10 mg) and approved in many countries since 1996. The tablets are no longer available today. For example, fexofenadine (Telfast) or another 2nd-generation antihistamine can be used as an alternative. Structure and properties Mizolastine (C24H25FN6O, Mr = 432.5 g/mol) a piperidine and benzimidazole derivative. It is … Mizolastine
Products Rimonabant was on the market in the form of film-coated tablets (Acomplia, Zimulti) starting in 2006. Because the drug can cause psychiatric disorders such as depression as a side effect, it was withdrawn from the market in 2008. Structure and properties Rimonabant (C22H21Cl3N4O, Mr = 463.8 g/mol) is a chlorinated piperidine and pyrazole carboxamide … Rimonabant
Products Lasmiditan was approved in the United States in 2019 in film-coated tablet form (Reyvow). Structure and properties Lasmiditan (C19H18F3N3O2, Mr = 377.4 g/mol) is present in the drug as lasmiditanhemisuccinate, a white crystalline powder that is sparingly soluble in water. It is a piperidine and pyridine derivative and has no indole structure. Effects Lasmiditan … Lasmiditan
Products Alogliptin is commercially available in film-coated tablet form as a monopreparation (Vipidia) and as a fixed combination with metformin (Vipdomet). It was approved in many countries in 2013. Structure and properties Alogliptin (C18H21N5O2, Mr = 339.4 g/mol) is present in drugs as alogliptin benzoate, a white crystalline powder that is sparingly soluble in water. … Alogliptin
Products Flecainide is commercially available as tablets and as a solution for injection (Tambocor). It has been approved in many countries since 1984. Structure and properties Flecainide (C17H20F6N2O3, Mr = 414.3 g/mol) is present in drugs as flecainide acetate, a white, crystalline, and very hygroscopic powder that is soluble in water. It is an amide-type … Flecainide