Products Zopiclone is commercially available in tablet form (Imovane, auto-generics). It has been approved in many countries since 1993. In the United States, the pure -enantiomer eszopiclone is also available (Lunesta). Structure and properties Zopiclone (C17H17ClN6O3, Mr = 388.8 g/mol) is a racemate and belongs to the cyclopyrrolones. It exists as a white to slightly … Zopiclone
Products Zileuton is commercially available in the United States in tablet and powder form (Zyflo). It is not currently approved in many countries. Structure and properties Zileuton (C11H12N2O2S, Mr = 236.3 g/mol) is an almost odorless, white, crystalline powder that is practically insoluble in water. It exists as a racemate. Both enantiomers are pharmacologically active. … Zileuton
Products Oxazepam is commercially available in tablet form (Seresta, Anxiolit). It has been approved in many countries since 1966. Structure and properties Oxazepam (C15H11ClN2O2, Mr = 286.7 g/mol) is a racemate. It exists as a white crystalline powder that is practically insoluble in water. Effects Oxazepam (ATC N05BA04) has antianxiety, sedative, sleep-inducing, anticonvulsant, and muscle … Oxazepam: Drug Effects, Side Effects, Dosage and Uses
Products Mirtazapine is commercially available in the form of film-coated tablets and meltable tablets (Remeron, generics). It has been approved in many countries since 1999. Structure and properties Mirtazapine (C17H19N3, Mr = 265.35 g/mol) is a racemate and exists as a white crystalline powder that is sparingly soluble in water. It is structurally closely related … Mirtazapine: Drug Effects, Side Effects, Dosage and Uses
Products Nadifloxacin is commercially available as a cream (Nadixa). The drug is not registered in many countries. It has been approved in Japan since 1993 and in Germany since 2000. Structure and properties Nadifloxacin (C19H21FN2O4, Mr = 360.4 g/mol) is a 3rd generation fluoroquinolone. The figure shows the more active -nadifloxacin; the cream contains the … Nadifloxacin
Products Biperiden is commercially available as tablets, sustained-release tablets, and a solution for injection (Akineton, Akineton retard). It has been approved in many countries since 1958. Structure and properties Biperiden (C21H29NO, Mr = 311.46 g/mol) is present in drugs as biperidene hydrochloride, a white crystalline powder that is sparingly soluble in water. It is a … Biperides
Products Bisoprolol is commercially available in film-coated tablet form as a monopreparation (Concor, generic) and as a fixed combination with hydrochlorothiazide (Concor plus, generic). It has been approved in many countries since 1986. In 2016, a fixed combination with perindopril was approved (Cosyrel). Structure and properties Bisoprolol (C18H31NO4, Mr = 325.4 g/mol) is present in … Bisoprolol Effects and Side Effects
Products In many countries, no drugs containing amphetamine are currently registered. The active ingredient is subject to narcotics legislation and requires an aggravated prescription, but is basically not prohibited like other substances from the amphetamine group. In some countries, medicines containing dexamphetamine are on the market, for example in Germany and the USA. Structure and … Amphetamine
Products Amphetamines are commercially available as drugs in the form of tablets, sustained-release tablets, capsules, and sustained-release capsules. Structure and properties Amphetamines are derivatives of amphetamine. It is a methylphenethylamine structurally related to endogenous monoamines and stress hormones epinephrine and norepinephrine. Amphetamines are racemates and the –enantiomers. Effects Amphetamines have sympathomimetic, central stimulant, bronchodilator, psychoactive, … Amphetamines
Products Sulpiride is commercially available in the form of capsules and tablets (Dogmatil). It has been approved in many countries since 1976. Structure and properties Sulpiride (C15H23N3O4S, Mr = 341.4 g/mol) is a racemate. It exists as a white crystalline powder that is practically insoluble in water. It belongs to the substituted benzamides. Effects Sulpiride … Sulpiride (Dogmatil): Drug Effects, Side Effects, Dosage and Uses
Products Benfluorex was marketed in many countries as Mediaxal (150 mg, Servier) until 1998. Today, it is no longer on the market. In France and other European countries, it was available as Mediator, among other products. Its approval was not withdrawn in France until 2009, although the risk for cardiotoxic side effects of comparable drugs … Benfluorex
Products Benoxaprofen was commercially available in tablet form (Oraflex, Opren) beginning in 1980. It was withdrawn from the market again in August 1982 because of the numerous adverse effects reported. Structure and properties Benoxaprofen (C16H12ClNO3, Mr = 301.7 g/mol) is a chlorinated benzoxazole derivative and exists as a racemate. It belongs to the propionic acid … Benoxaprofen