Oral Mucositis

Symptoms Oral mucositis manifests as redness, swelling, pain, a burning sensation, aphthae, a white to yellowish coating, sores, ulceration, bleeding, and bad breath, among other symptoms. The tongue and gums may also be affected. The discomfort may increase in association with eating. Sores can be so painful that food intake is limited, which can lead … Oral Mucositis

Lesinurad

Products Lesinurad was approved in the US in 2015, in the EU in 2016, and in many countries in 2017 in film-coated tablet form (Zurampic). A fixed-dose combination with allopurinol was released in the US in 2017 (Duzallo), in the EU in 2018, and in many countries in 2019. Structure and properties Lesinurad (C17H14BrN3O2S, Mr … Lesinurad

Willow Bark Health Benefits

Stem plant Salicaceae, another Salix sp., silver willow. Medicinal drug Salicis cortex, willow bark. Willow bark consists of the whole or cut dried bark of young twigs or whole dried pieces of young twigs of the current year of various species of the genus , including L., Vill. and L. (PhEur). PhEur requires a minimum … Willow Bark Health Benefits

Calcium Carbase Salad

Products Calcium carbasalate (carbasalate calcium) is commercially available in the form of tablets and effervescent tablets (Alcacyl, Alca C with vitamin C). It has been approved in many countries since 1935. Note: Alcacyl powder contains lysine acetyl salicylate. Structure and properties Calcium carbasalate (C19H18CaN2O9, Mr = 458.4 g/mol) exists as a white crystalline powder that … Calcium Carbase Salad

Mercaptopurine

Poducts Mercaptopurine is commercially available in tablet and oral suspension form (Puri-Nethol, Xaluprine). The active ingredient has been approved in many countries since 1955. Structure and properties Mercaptopurine (C5H4N4S – H2O, Mr = 170.2 g/mol) exists as a yellow crystalline powder that is practically insoluble in water. It is an analog of the purine bases … Mercaptopurine

Mesalazine

Products Mesalazine is commercially available as film-coated tablets, enteric-coated sustained-release tablets, granules, sustained-release granules, clysms, and suppositories (e.g., Asacol, Mezavant, Pentasa, Salofalk). It has been approved in many countries since 1984. Structure and properties Mesalazine (C7H7NO3, Mr = 153.1 g/mol) corresponds to 5-aminosalicylic acid (5-ASA). The active ingredient exists as powders or crystals that are … Mesalazine

Teething Discomfort

Background The first baby teeth usually appear between 6 and 12 months of age. Rarely, they erupt before 3 months of age or not until after 12 months of age. After 2 to 3 years at the latest, all teeth have erupted. Symptoms Numerous signs and symptoms are traditionally attributed to teething. However, a causal … Teething Discomfort

Traveler’s Diarrhea

Symptoms Traveler’s diarrhea is usually defined as a diarrheal illness that occurs in travelers from industrialized countries during or after a visit to a high-risk area, such as Latin America, Africa, the Middle East, or Asia. It is the most common travel illness, affecting 20% to 60% of travelers. Depending on the pathogen and severity, … Traveler’s Diarrhea

Diethylamine Salicylate

Effects Diethylamine salicylate (ATC M02AC) has analgesic and anti-inflammatory properties. Indications For local treatment of inflammation, pain, bruising, and swelling, e.g., secondary to sprains, contusions, and strains.

Diflunisal

Products Diflunisal is no longer available in pharmaceuticals in many countries. Unisal is out of commerce. Structure and properties Diflunisal (C13H8F2O3, Mr = 250.2 g/mol) is a derivative of salicylic acid. It exists as a white crystalline powder that is practically insoluble in water. Effects Diflunisal (ATC N02BA11) is analgesic, antipyretic, and anti-inflammatory. Indications Pain, … Diflunisal

Aphthae

Symptoms Aphthae are usually small, approximately lentil-sized, white to yellow fibrin-covered, flat erosions and ulcerations of the oral mucosa. The marginal region is slightly raised and reddened. Aphthae occur in one or more locations and are particularly painful on contact with acidic or spicy foods. The so-called herpetiform aphthae are smaller and more numerous than … Aphthae

Enteric-Coated Tablets

Products Several drugs are commercially available as enteric-coated tablets. Listed below are active ingredients that are administered with this dosage form: Proton pump inhibitors such as pantoprazole and esomeprazole. Some painkillers, e.g., NSAIDs such as diclofenac Digestive enzymes: pancreatin Laxative: bisacodyl Salicylates: mesalazine, acetylsalicylic acid 100 mg. Structure and properties Enteric coated tablets belong to … Enteric-Coated Tablets