Products Nintedanib was approved in many countries in 2015 in soft capsule form (Ofev). Structure and properties Nintedanib (C31H33N5O4, Mr = 539.6 g/mol) is present in the drug as nintedanibesilate, a light yellow powder. Effects Nintedanib (ATC L01XE31) has antiproliferative and antitumor properties. It inhibits intracellular signaling pathways responsible for fibroblast proliferation, migration, and transformation. … Nintedanib
Products Docusate sodium is commercially available in many countries in the form of soft capsules and as ear drops, among other products. It is not registered as a laxative in many countries. Structure and properties Docusate sodium (C20H37NaO7S, Mr = 444.6 g/mol) exists as white, hygroscopic, and waxy flakes or masses and is sparingly soluble … Docusate Sodium
Products Lubiprostone is commercially available in the form of soft capsules (Amitiza). It has been approved in many countries since 2009. Structure and properties Lubiprostone (C20H32F2O5, Mr = 390.46) is a white, odorless powder that is insoluble in water and soluble in ethanol and ether. It is a derivative of a metabolite of prostaglandin E1. … Lubiproston
Products Palonosetron is commercially available as a solution for injection and as soft capsules (Aloxi, generic). It has been approved in many countries since 2006. The capsules were registered in 2013. Also approved is a fixed combination of netupitant and palonosetron in capsule form; see netupitant palonosetron. Structure and properties Palonosetron (C19H24N2O, Mr = 296.4 … Palonosetron
Products Vitamin E is contained in numerous medicines, dietary supplements and cosmetics, for example in the form of soft capsules. Structure and properties Vitamin E exists as a clear, colorless to yellowish brown, viscous, oily liquid and is practically insoluble in water. In contrast, it is readily soluble in fatty oils (fat-soluble vitamin). It is … Vitamin E
Products Cineol is approved as a monopreparation in the form of soft capsules (Soledum / Soledum forte). In many countries, the capsules were registered in 2018. In Germany, the product has been available for some time. In addition, combination preparations are also available. Cineol is also contained in eucalyptus oil. This article refers to the … Cineol
Products Diclofenac is commercially available in the form of tablets, capsules, soft capsules (liquid caps), dragées, drops, suppositories, as a solution for injection, gel, patches, and eye drops (Voltaren, generics), among others. The analgesic has been approved in many countries since 1974. This article refers to peroral use. For more information, see also diclofenac gel, … Diclofenac: Drug Effects, Side Effects, Dosage and Uses
Products Midostaurin was approved in many countries, in the EU and in the US in 2017 in the form of soft capsules (Rydapt). Structure and properties Midostaurin (C35H30N4O4, Mr = 570.6 g/mol) is a -benzoyl derivative of staurosporine, an alkaloid isolated from the bacterium. The two active metabolites CGP62221 and CGP52421 are involved in the … Midostaurin
Products Serotonin receptor antagonists are commercially available in the form of film-coated tablets, melting tablets, soft capsules, as syrups, and as infusion/injection preparations. This article refers to the setrone (5-HT3 receptor antagonists), which are used as antiemetics. The first agent from this group to be approved in the United States was ondansetron (Zofran) in 1991, … Serotonin Antagonists (Setrone)
Products Lavender oil soft capsules have been approved as medicinal products in many countries since 2016 (Lasea, Laitea). In Germany, the product was already approved in 2010. Ingredients The capsules contain the defined lavender oil Silexan (WS 1265) from the narrow-leaved medicinal lavender and pharmaceutical excipients. Silexan complies with the specifications of the European Pharmacopoeia … Lavender Oil Capsules
Products Butylated hydroxyanisole is found in numerous drugs as an excipient, for example in semisolid and liquid dosage forms, as well as in tablets and soft capsules. Structure and properties Butylated hydroxyanisole (C11H16O2, Mr = 180.3 g/mol) exists as a white to yellowish or faintly pinkish crystalline powder that is practically insoluble in water. It … Butylhydroxyanisole
Products Butylated hydroxytoluene is found in pharmaceuticals as an excipient, mainly in semisolid and liquid medicines, but also in some tablets, soft capsules, and medicated chewing gum, for example. Structure and properties Butylhydroxytoluene (C15H24O, Mr = 220.4 g/mol) exists as a white to yellowish white crystalline powder and is practically insoluble in water due to … Butylhydroxytoluene
