Products Chlortalidone is commercially available in tablet form (combination products). It has been approved in many countries since 1967. This article refers to the monopreparations. Hygroton (Novartis) was discontinued in many countries in 2014. Structure and properties Chlortalidone (C14H11ClN2O4S, Mr = 338.77 g/mol) is a racemate. It exists as a white to yellowish white powder … Chlortalidone
Products Indapamide is commercially available as tablets and capsules alone in sustained-release formulations (Fludex SR, generic) and in combination with the ACE inhibitor perindopril (Coversum N Combi, generic). A fixed combination of perindopril, indapamide, and amlodipine is also available (Coveram plus). Indapamide was developed in the 1970s and has been approved in many countries since … Indapamide
Products Acetazolamide is commercially available in tablet form and as an injectable (Diamox, Glaupax). It has been approved in many countries since 1955. Structure and properties Acetazolamide (C4H6N4O3S2, Mr = 222.2 g/mol) exists as a white crystalline powder that is very sparingly soluble in water. The sodium salt acetazolamide sodium, which is present in the … Acetazolamide
Products Riboflavin (vitamin B2) is contained in numerous drugs and dietary supplements and is commercially available, for example, in the form of tablets, effervescent tablets, lozenges, as an injection preparation, and as a juice. Most of the products are combination preparations with other vitamins, minerals and trace elements. Riboflavin is contained in many plant and … Riboflavin
Products Pyrimethamine is commercially available in tablet form (Daraprim). The combination Fansidar (+ sulfadoxine) is off the market (malaria). Structure and properties Pyrimethamine (C12H13ClN4, Mr = 248.7 g/mol) is a diaminopyrimidine. It exists as a white crystalline powder or as colorless crystals and is practically insoluble in water. Effects Pyrimethamine (ATC P01BD01) has antiparasitic properties. … Pyrimethamine
Products Mavacoxib is commercially available in the form of chewable tablets for dogs (Trocoxil). It has been approved in many countries since 2009. Structure and properties Mavacoxib (C16H11F4N3O2S, Mr = 385.3 g/mol) is a pyrazole benzenesulfonamide that exists as a white to off-white powder. It is nearly insoluble in water at a pH between 1.2 … Mavacoxib
Products Tetracaine is commercially available in the form of eye drops (Tetracaine). It has been approved in many countries since 1987. Structure and properties Tetracaine (C15H24N2O2, Mr = 264.4 g/mol) is present in drugs as tetracaine hydrochloride, a white, crystalline, and slightly hygroscopic powder that is readily soluble in water. It belongs to the ester-type … Tetracaine (Eye Drops)
Products Oxybuprocaine eye drops 0.4% (4 mg/ml) have been approved in many countries since 1971. They are commercially available as a monopreparation (Novesin, Cebesin, Oxybuprocaine SDU Faure) and in combination with fluorescein (Fluoresceine-Oxybuprocaine SDU Faure). Structure and properties Oxybuprocaine is present in drugs as oxybuprocaine hydrochloride (C17H29ClN2O3, Mr = 344.9) is present. It is a … Oxybuprocaine Eye Drops
Products Naproxen has been approved in many countries since 1975 and is commercially available in the form of film-coated tablets (e.g., Apranax, Proxen, generics). Other dosage forms such as the suppositories and the juice are no longer available. Drugs with a deep dose have been available over the counter since 1999 (Aleve with 200 mg … Naproxen: Drug Effects, Side Effects, Dosage and Uses
Sulfonamides represent synthetic chemical antibiotics that prevent bacteria from multiplying. Today, they are rarely used in humans because of their rather weak mode of action and many side effects. To prevent resistance, combination preparations of sulfonamides with diaminopyrimidines are usually used. What are sulfonamides? Sulfonamides represent synthetic chemical antibiotics that prevent bacteria from multiplying. Sulfonamides … Sulfonamides: Effect, Uses & Risks
