Products Zonisamide is commercially available in the form of capsules (Zonegran). It has been approved in many countries since 2006. Structure and properties Zonisamide (C8H8N2O3S, Mr = 212.2 g/mol) is a benzisoxazole derivative and a sulfonamide. It exists as a white powder that is soluble in water. Effects Zonisamide (ATC N03AX15) has anticonvulsant and antiepileptic … Zonisamide
Products Sulfadiazine is commercially available in combination with silver as silver sulfadiazine cream and gauze (Flammazine, Ialugen plus). This article refers to internal use. See also under silver sulfadiazine. Structure and properties Sulfadiazine (C10H10N4O2S, Mr =250.3 g/mol) exists as in the form of crystals or as a crystalline powder with white, yellowish or light pink … Sulfadiazine
Products Sulfadimethoxine is commercially available in the form of drops (Relardon). It has been approved in many countries since 1970. Structure and properties Sulfadimethoxine (C12H14N4O4S, Mr = 310.3 g/mol) is a sulfonamide. Effects Sulfadimethoxine (ATCvet QJ01EQ09) is bacteriostatic and antiprotozoal. The effects are due to inhibition of parasite folic acid synthesis. Indications For the treatment … Sulfadimethoxine
Products Currently, drugs containing sulfadimidine are no longer on the market in many countries. Structure and properties Sulfadimidine (C12H14N4O2S, Mr = 278.3 g/mol) is a sulfonamide. It exists as white crystals or as a white powder and is very sparingly soluble in water. Effects Sulfadimidine (ATCvet QJ01EQ03) is antibacterial. Indications Bacterial infectious diseases (veterinary drug).
Products Sulfaguanidine is commercially available in combination preparations as a powder for animals. Structure and properties Sulfaguanidine (C7H10N4O2S, Mr = 214.2 g/mol) is a sulfonamide and guanidine derivative. Effects Sulfaguanidine (ATCvet QA07AB03) has antibacterial properties. It acts mainly locally in the digestive tract, as it is hardly absorbed into the organism. Indications Diarrheal diseases in … Sulfaguanidine
Products Sulfasalazine is commercially available as tablets and as dragées with an enteric coating (salazopyrin, salazopyrin EN, some countries: azulfidine, azulfidine EN, or RA). It has been approved in many countries since 1950. EN stands for enteric coated and RA for Rheumatoid Arthritis. EN dragées have a coating to prevent irritation and improve gastric tolerance. … Sulfasalazine: Drug Effects, Side Effects, Dosage and Uses
Effect Antibacterial Bakeriostatic Antiparasitic against protozoa Mechanism of action Sulfonamides inhibit the synthesis of folic acid in microorganisms. They are structural analogues (antimetabolites) of the natural substrate p-aminobenzoic acid and competitively displace it. Trimethoprim, used in combination with sulfamethoxazole, has a synergistic effect. Indications Bacterial infectious diseases caused by: Streptococcus Pneumococcus Actinomycetes Nocardia, e.g. nocaridosis … Sulfonamides
Products Cefalexin is commercially available as a veterinary drug in the form of tablets, chewable tablets, and suspensions. It is available both as a monopreparation (e.g., Cefacat, Cefadog) and in combination with kanamycin (Ubrolexin). It has been approved in many countries since 1986. Structure and properties Cefalexin (C16H17N3O4S , Mr = 347.4 g/mol) exists as … Cefalexin
Products Sultiam is commercially available in the form of film-coated tablets (Ospolot). It has been approved in many countries since 2003. In Germany, it was approved as early as 1998. In English, it is also referred to as resp. Structure and properties Sultiam (C10H14N2O4S2, Mr = 290.4 g/mol) is a sulfonamide derivative that is structurally … Sultiam
Products Thiazide diuretics are commercially available in tablet form. Chlorothiazide (Diuril) and the closely related and more potent hydrochlorothiazide were the first of this group to enter the market in the 1950s (Switzerland: Esidrex, 1958). However, other related thiazide-like diuretics are available (see below). In English, we speak of (thiazide diuretics) and (thiazide-like diuretics). Numerous … Thiazide Diuretics
Products Dapsone is approved in Germany in tablet form (Dapsone-Fatol). In the USA, it is additionally on the market as a gel for the treatment of acne (Aczone). No preparations are currently registered in many countries. Structure and properties Dapsone or 4,4′-diaminodiphenylsulfone (C12H12N2O2S, Mr = 248.3 g/mol) is a sulfone and aniline derivative with structural … Dapsone
Products Gliclazide has been commercially available in sustained-release tablet form and approved in many countries since 1978. The sustained-release dosage forms entered the market in 2001. In addition to the original Diamicron MR, sustained-release generics have been available since 2008. Sales of the non-retarded Diamicron 80 mg were discontinued in 2012. Structure and properties Gliclazide … Gliclazide
