Products Darunavir is commercially available as film-coated tablets and as an oral suspension (Prezista). It has been approved in many countries since 2006. In 2016, a fixed-dose combination with cobicistat was approved (Rezolsta film-coated tablets). In 2018, generic versions of the tablets entered the market. Structure and properties Darunavir (C27H37N3O7S, Mr = 547.7 g/mol) is … Darunavir
Products Carbamazepine is commercially available as tablets, sustained-release tablets, suspension, and syrup (Tegretol, generics). It has been approved in many countries since 1963. Structure and properties Carbamazepine (C15H12N2O, Mr = 236.3 g/mol) exists as a white crystalline powder that is very sparingly soluble in water. It has a tricyclic structure and an active metabolite, carbmazepine-10,11-epoxide. … Carbamazepine Effects and Side Effects
Products Onasemnogene bebeparvovec was approved in the United States in 2019 as a suspension for intravenous infusion (Zolgensma). Structure and properties It is a gene therapy using the -gene, in which adeno-associated serotype 9 (AAV9) viruses are used as vectors. The gene is contained in the form of double-stranded DNA in the capsid of the … Onasemnogen-Abeparvovec
Products Dried apple powder is commercially available as a powder to prepare a suspension for ingestion. It was approved in many countries in 2015. In Germany, it was available earlier (Aplona). Structure and properties The powder is made from dried and unpeeled apples with excipients. Active ingredients include the gelling agent pectin. Effects Apple powder … Apple Powder
Products Febantel is commercially available in combination tablet and suspension form as a veterinary drug. It has been approved in many countries since 1988. Structure and properties Febantel (C20H22N4O6S, Mr = 446.5 g/mol) is a sample zimidazole and a guanidine derivative. It exists as a colorless powder and is insoluble in water and alcohol due … Febantel
Products Felbamate is commercially available in tablet and suspension form (Taloxa). It has been approved in many countries since 1997. Structure and properties Felbamate (C11H14N2O4, Mr = 238.2 g/mol) is a dicarbamate. It exists as a white crystalline powder with a typical odor that is sparingly soluble in water. Effects Felbamate (ATC N03AX10) has antiepileptic … Felbamate
Products Fenbendazole is commercially available as granules, paste, powder, bolus, suspension, and tablets, among others. It has been approved in many countries since 1976. Structure and properties Fenbendazole (C15H13N3O2S, Mr = 299.3 g/mol) is a benzimidazole derivative. It exists as a white powder that is practically insoluble in water. Effects Fenbendazole (ATCvet QP52AC13) has antihelminthic … Fenbendazole
Products Hydrotalcite was approved in many countries since 1992 and was commercially available as a suspension (Rennie Gel Hydrotalcite, off label). In Germany, it is also available as chewable tablets (Talcid, generic). Structure and properties Hydrotalcite (Al2Mg6(OH)16CO3 – 4H2O, Mr = 531.9 g/mol) is a magnesium aluminum hydroxide carbonate hydrate with a layered lattice structure. … Hydrotalcite
Definition A concentration (C) indicates the content of one substance in another as a quotient. By definition, it refers to the amount of a substance present in a given volume. However, concentrations can also refer to masses. In pharmacy, concentration is often used in connection with liquid and semisolid dosage forms. For solid dosage forms … Concentration
Products Brinzolamide is form of eye drops commercially available (Azopt) and approved in many countries since 1991. Generic versions were released in 2015. Brinzolamide has also been available in a fixed combination with timolol since 2009 (Azarga). In 2015, a fixed combination with brimonidine was approved; see brinzolamide brimonidine (Simbrinza). Structure and properties Brinzolamide (C12H21N3O5S3, … Brinzolamide
Products Sodium alginate, along with sodium bicarbonate and calcium carbonate, is commercially available as chewable tablets and as a suspension (Gaviscon). It was approved in many countries in 2013. Structure and properties Sodium alginate is mainly composed of the sodium salt of alginic acid. Alginic acid is a mixture of polyuronic acids with alternating proportions … Sodium Alginate
Products Astemizole was commercially available in tablet and suspension form (Hismanal). It has been withdrawn from the market in many countries because of potential adverse effects and is no longer available (see below). It may well be replaced by other, better-tolerated antihistamines, such as cetirizine, loratadine, and fexofenadine. Structure and properties Astemizole (C28H31FN4O, Mr = … Astemizole
