Propiverine

Products Propiverine was approved in many countries in 2020 in the form of modified-release hard capsules (Mictonorm). Later, coated tablets were also registered (Mictonet). This is an older active ingredient that was available earlier in Germany, for example. Structure and properties Propiverine (C23H29NO3, Mr = 367.5 g/mol) is present in drugs as propiverine hydrochloride. Active … Propiverine

Antiallergics

Products Anti-allergy medications are available in numerous dosage forms. These include tablets, capsules, solutions, suspensions, nasal sprays, eye drops, inhalation preparations, and injectables. Structure and properties Antiallergic drugs do not have a uniform chemical structure. However, several groups within the class can be identified (see below). Effects Antiallergic drugs have antiallergic, antiinflammatory, immunosuppressive, antihistamine, and … Antiallergics

Beta2-Sympathomimetics

Products Beta2-sympathomimetics are usually commercially available as inhalation preparations (powders, solutions) administered with an inhaler, for example, metered-dose inhaler, diskus, Respimat, Breezhaler, or Ellipta. There are few drugs on the market that can be given perorally. Structure and properties Beta2-sympathomimetics are structurally related to the natural ligands epinephrine and norepinephrine. They may exist as racemates … Beta2-Sympathomimetics

Glaucoma: Causes and Treatment

Symptoms Glaucoma is a progressive eye disease that is initially asymptomatic. Patients have no symptoms until the optic nerve becomes increasingly damaged, which can lead to irreversible visual impairment with visual field loss and blindness. Glaucoma represents the most common cause of blindness. Causes The cause of the disease is usually an increase in intraocular … Glaucoma: Causes and Treatment

Sympathomimetics

Products Sympathomimetics are commercially available, for example, in the form of tablets, capsules, granules, injectable solutions, eye drops, and nasal sprays. Structure and properties Sympathomimetics are structurally derived from the natural neurotransmitters epinephrine and norepinephrine. Effects Sympathomimetics have sympathomimetic properties, meaning that they promote the effects of the sympathetic nervous system, a portion of the … Sympathomimetics

Olodaterol

Products Olodaterol was approved in many countries in 2014 as a solution for inhalation (Striverdi). In 2016, a fixed-dose combination with tiotropium bromide was also marketed (Spiolto). Both drugs are administered with the Respimat. Respimat The Respimat is a new inhalation device that releases a visible spray, or aerosol. The droplets are fine and move … Olodaterol

Tramazoline

Products Tramazoline is commercially available in the form of nasal sprays, nasal drops, and as eye drops. The drugs are not registered in many countries. Structure and properties Tramazoline (C13H17N3, Mr = 215.3 g/mol) is an imidazoline derivative structurally related to naphazoline, oxymetazoline, and xylometazoline. Effects Tramazoline (ATC S01GA) is a vasoconstrictor and decongestant. The … Tramazoline

Enalapril: Drug Effects, Side Effects, Dosage and Uses

Products Enalapril is commercially available in tablet form (Reniten, generics). It has been approved in many countries since 1984. The active ingredient is also combined fixed with hydrochlorothiazide. Structure and properties Enalapril (C20H28N2O5, 376.45 g/mol) is present in drugs as enalapril maleate, a white powder that is sparingly soluble in water. Enalapril is the prodrug … Enalapril: Drug Effects, Side Effects, Dosage and Uses

Cave Canem: Caniphedrine

Caniphedrine The alkaloid L-ephedrine is found along with other alkaloids in plants of the genus Ephedra (e.g., Stapf, Ephedraceae). The herb has been used in Chinese medicine under the name Ma Huang for over 5000 years. In the 16th century pharmacopoeia Pentsao Kang Mu by Li Shih-Chen, it is recommended as a circulatory stimulant, diaphoretic, … Cave Canem: Caniphedrine

Fear of Injections

Symptoms Shortly after an injection, some patients may experience the following symptoms: Pallor Malaise Dry mouth Cold sweat Low blood pressure Drowsiness, dizziness, confusion Nausea Fainting, syncope (short-lasting circulatory collapse). Convulsions (seizures) ECG changes Falls, accidents These disorders occur, for example, shortly after a vaccination, after parenteral administration of drugs, during acupuncture or blood sampling. … Fear of Injections

Formoterol

Products Formoterol is commercially available in the form of capsules for inhalation (Foradil) and as a powder inhaler (Oxis). Furthermore, combination products with budesonide (Symbicort Turbuhaler, Vannair Dosieraerosol) and fluticasone propionate are available (Formoterol Dosieraerosol). Formoterol is also combined with beclometasone fixed, see under beclometasone and formoterol (Foster). Furthermore, in 2020, a fixed combination with … Formoterol