Products Bases are available as pure substances in pharmacies and drugstores. They are included in numerous medicines as active ingredients and excipients. Definition Bases (B) are proton acceptors. They accept a proton from an acid (HA), a proton donor, in the acid-base reaction. Thus, they lead to deprotonation: HA + B ⇄ HB + + … Bases
Products Bazedoxifene is commercially available in the form of film-coated tablets (Conbriza). It has been approved in many countries since 2010. In 2015, a fixed combination with conjugated estrogens was registered (Duavive). This article refers to monotherapy. Structure and properties Bazedoxifene (C30H34N2O3, Mr = 470.60 g/mol) is a nonsteroidal selective estrogen receptor modulator developed from … Bazedoxifene
Products Refined palm oil is found in countless processed foods, including margarine, biscuits, potato chips, spreads (e.g. Nutella), ice cream and sweets. The palms are grown mainly in Malaysia and Indonesia. Annual production is in the range of over 50 million tons. No other vegetable oil is produced in greater quantities. Structure and properties Palm … Palm Oil
Triglycerides represent triple esters of glycerol with fatty acids. They are used by many organisms to store energy. In the human organism, they are the main component of adipose tissue. What are triglycerides? Triglycerides contain three fatty acids esterified with glycerol in the molecule. Here, the prefix “tri” already indicates the number of fatty acid … Triglycerides: Function & Diseases
Products Rosuvastatin is commercially available in the form of film-coated tablets (Crestor, generic, auto-generic). It was approved in many countries in 2006 (Netherlands: 2002, EU and US: 2003). The marketing authorization holder is AstraZeneca. The statin was originally developed at Shionogi in Japan. In the USA, generic versions came on the market in 2016. In … Rosuvastatin
Products Ciprofibrate was commercially available in many countries in capsule form (Hyperlipen, off label). It was approved in 1993 and has not been available since 2013. Structure and properties Ciprofibrate (C13H14Cl2O3, Mr = 289.2 g/mol) is a racemate and a phenoxyisobutyric acid derivative. It exists as a white to pale yellow powder that is practically … Ciprofibrate
Products Fluvastatin is commercially available in the form of capsules and sustained-release generic tablets (generics). It has been approved in many countries since 1993. Sales of the original Lescol were discontinued by Novartis in 2018. Structure and properties Fluvastatin (C24H26FNO4, Mr = 411.5 g/mol) is present in drugs as fluvastatin sodium, a white or pale … Fluvastatin
Products Medium-chain triglycerides are found as excipients in liquid, semisolid, and solid drug products. Structure and properties Medium-chain triglycerides are a mixture of triglycerides of saturated fatty acids, which mainly include caprylic acid (C8) and capric acid (C10). They are obtained from coconut or palm oil. It is a colorless to slightly yellowish oily liquid … Medium Chain Triglycerides
Products Pitavastatin is commercially available in the form of film-coated tablets (Livazo). It was first approved in many countries in July 2012. In Japan, it has been on the market since 2003, and it is also available in other countries such as the United States and Germany. Structure and properties Pitavastatin (C25H24FNO4, Mr = 421.5 … Pitavastatin
Products Lecithin is available in specialty stores. It is found in many pharmaceuticals as an excipient, as well as an additive in foods, and is available as a dietary supplement. Structure and properties Lecithins exist as brown granules or viscous liquids and have amphiphilic properties, meaning they have both hydrophilic and lipophilic structural components. They … Lecithin
Products Acipimox is commercially available in the form of capsules (Olbetam). It has been approved in many countries since 1986. Structure and properties Acipimox (C6H6N2O3, Mr = 154.1 g/mol) is a derivative of nicotinic acid, which is also active as a lipid-lowering agent. Effects Acipimox (ATC C10AD06) has lipid-lowering properties. It lowers triglycerides, cholesterol, LDL, … Acipimox
Products Fats for medical use and medicines and dietary supplements made from them are available in pharmacies and drugstores. They are also available in grocery stores. Fats are also called butter, such as shea butter. Structure and properties Fats are semi-solid to solid and lipophilic mixtures of substances (lipids) consisting mainly of triglycerides. These are … Bold
