Products Erenumab was approved in many countries, in the EU, and in the United States in 2018 as a solution for injection in a prefilled pen and a prefilled syringe (Aimovig, Novartis / Amgen). Structure and properties Erenumab is a human IgG2 monoclonal antibody directed against the CGRP receptor. It has a molecular weight of … Erenumab
Products Dihydropyridines are commercially available in many countries in the form of film-coated tablets, sustained-release tablets, capsules, and injectables. Nifedipine from Bayer (Adalat) was the first active ingredient from this group to enter the market in the mid-1970s. Today, amlodipine (Norvasc, generics) is most commonly prescribed. Structure and properties The name 1,4-dihydropyridines is derived from … Dihydropyridine
Products Diltiazem is commercially available in tablet and capsule form (Dilzem, generic). It has been approved in many countries since 1982. Structure and properties Diltiazem (C22H26N2O4S, Mr = 414.52 g/mol) is a benzothiazepine derivative. It is present in drugs as diltiazem hydrochloride, a white crystalline powder with a bitter taste that is readily soluble in … Diltiazem
Products Most sartans are commercially available as tablets or film-coated tablets. Losartan was the first agent approved in many countries in 1994 (Cosaar, USA: 1995, Cozaar). Sartans are often combined with hydrochlorothiazide fix. The name of the drug group is derived from the suffix -sartan of the active ingredients. The drugs are also called angiotensin … Sartans
Products Cyclandelate was commercially available in many countries in the form of dragées (Cyclandelat Streuli). It was approved in 1973 and went out of commerce in 2012. Structure and properties Cyclandelate (C17H24O3, Mr = 276.4 g/mol) Effects Cyclandelate (ATC C04AX01) has vasodilator properties. It has a direct papaverine-like effect on smooth muscle, particularly that of … Cyclandelate
Products Tadalafil is commercially available in the form of film-coated tablets (Cialis, Adcirca, generics). It has been approved in many countries since 2004. Generics were registered in 2016 and came on the market in 2019. This article is related to erectile dysfunction treatment. Structure and properties Tadalafil (C22H19N3O4, Mr = 389.4 g/mol) exists as a … Tadalafil
Products Prazosin is commercially available in some countries in tablet form. It is no longer approved in many countries. Structure and properties Prazosin (C19H21N5O4, Mr = 383.4 g/mol) is a quinazoline derivative. It is present in drugs as prazosin hydrochloride, a white crystalline substance that is sparingly soluble in water. Effects Prazosin (ATC C02CA01) is … Prazosin
Products Diltiazem ointments are not registered as finished drug products in many countries. However, they can be prepared as an extemporaneous prescription in a pharmacy. Typically, two-percent dosage forms are used (gel, cream, or ointment). There are various manufacturing instructions. For example, white petroleum jelly, Excipial oily ointment, DAC base cream, or a gel base … Diltiazem Ointment
Products Dimethyl sulfoxide is approved as a drug in many countries and is sold exclusively in combination with other active ingredients. They are sprays, gels and creams. DMSO ointment 50% is produced in pharmacies. The pure substance is available in pharmacies and drugstores. Medicines for ingestion are not released. The metabolite MSM is available as … Dimethyl Sulfoxide (DMSO)
Products Capsaicin is commercially available in many countries as creams and patches, among other products. Capsaicin cream at 0.025% and 0.075% is not commercially available as a finished drug product. It is produced as a magisterial formulation in pharmacies. See also under the article capsaicin cream. Structure and properties Capsaicin (C18H27NO3, Mr = 305.4 g/mol) … Capsaicin
Products Capsaicin cream at 0.025% or 0.075% (also 0.1%) is not registered as a finished drug in many countries, unlike other countries. It is produced as an extemporaneous preparation in pharmacies. The specialized trade can also order them from specialized service providers. On the other hand, patches containing the active ingredient (Qutenza) are approved as … Capsaicin Cream
Products Felodipine is commercially available in the form of sustained-release tablets. In addition to the original Plendil, generic versions are also available. It has been approved in many countries since 1988. Structure and properties Felodipine (C18H19Cl2NO4, Mr = 384.3 g/mol) is a dihydropyridine. It exists as a white to pale yellow crystalline powder that is … Felodipine
