Desoximetasone

Products In many countries, medicines containing desoximetasone (formerly topisolone ointment) are no longer on the market. In other countries, the ointment is available. Structure and properties Desoximetasone (C22H29FO4, Mr = 376.5 g/mol) Effects Desoximetasone (ATC D07AC03 is a potent topical class III glucocorticoid with anti-inflammatory, antiallergic, and immunosuppressive effects. Indications For the treatment of inflammatory … Desoximetasone

Flumetasone Pivalate

Products Flumetasone pivalate is commercially available as a cream and ointment (locacortene, locasalen + salicylic acid). It has been approved in many countries since 1964. Structure and properties Flumetasone pivalate (C27H36F2O6, Mr = 494.6 g/mol) exists as a white crystalline powder that is practically insoluble in water. The steroid is twice fluorinated. Effects Flumetasone pivalate … Flumetasone Pivalate

Clobetasol Propionate

Products Clobetasol propionate is commercially available as cream, ointment, foam, shampoo, and scalp application (Dermovate, Clobex, Clarelux). It has been approved in many countries since 1976. Structure and properties Clobetasol propionate (C25H32ClFO5, Mr = 466.97 g/mol) is the ester of clobetasol with propionic acid. It is a derivative of prednisolone. Clobetasol propionate exists as a … Clobetasol Propionate

Clobetasone Butyrate

Products Clobetasone butyrate is commercially available as a cream and ointment (Emovate). It has been approved in many countries since 1980. Structure and properties Clobetasone butyrate (C26H32ClFO5, Mr = 479.0 g/mol) exists as a white powder that is practically insoluble in water. It has structural similarities to betamethasone. Clobetasone butyrate is a halogenated and esterified … Clobetasone Butyrate