Oxerutin

Products Venoruton Effects Oxerutin increases the resistance of capillary walls and promotes normalization of their permeability Indications Chronic venous insufficiency Postphlebitic syndrome Trophic disorders Varicose dermatitis Adjuvant after sclerosing treatment and exheresis of varicose veins and in leg ulcers. Symptoms of hemorrhoids Dosage According to the package insert. Contraindications Hypersensitivity First trimester of pregnancy Children … Oxerutin

Diosmin and Hesperidin

Products Diosmin and hesperidin are commercially available combined in the form of film-coated tablets (Daflon). It has been approved in many countries since 1977. Structure and properties Diosmin (C28H32O15, Mr = 608.5 g/mol): Hesperidin (C28H34O15, Mr = 610.6 g/mol): Effects Diosmin and hesperidin strengthen veins and protect blood vessels. Indications For treatment of edema and … Diosmin and Hesperidin

Naftazone

Products Naftazone is commercially available in the form of film-coated tablets (Mediaven, Mediaven forte). It has been approved in many countries since 1973. Structure and properties Naftazone (C11H9N3O, Mr = 215.21 g/mol) Effects Naftazone (ATC C05B) increases venous tone and inhibits iysosomal enzymes in the vein wall. Indications All forms of venous insufficiency Diabetic retinopathy … Naftazone

Calcium Dobesilate

Products Calcium dobesilate is commercially available in many countries as an ointment and in capsule form (Doxium, Doxiproct). Effects Calcium dobesilate (ATC C05BX01) improves capillary function and blood flow properties. Indications Microangiopathies, e.g., diabetic retinopathy. Chronic venous insufficiency As an adjuvant in superficial thrombophlebitis. Hemorrhoids Postthrombotic syndrome Microcirculatory disorders of arterio-venous origin Contraindications Calcium dobesilate … Calcium Dobesilate

Tribenoside

Products Tribenoside is commercially available as a cream and as suppositories (Procto-Glyvenol, fixed combination). It has been approved in many countries since 1972. Structure and properties Tribenoside (C29H34O6, Mr = 478.6 g/mol) exists as a yellowish to pale yellow, clear, viscous liquid and is practically insoluble in water. Effects Tribenoside (ATC C05AD01) reduces capillary permeability, … Tribenoside

Troxerutin

Products Troxerutin was commercially available in the form of film-coated tablets and capsules. It had been approved in many countries since 1977. Structure and properties Troxerutin (C33H42O19, Mr = 742.7 g/mol) or trihydroxyethylrutoside is a flavonoid. Effects Troxerutin (ATC C05CA04) stabilizes the permeable vascular walls of blood capillaries. Indications Chronic venous insufficiency Varicose early symptoms … Troxerutin