HPV vaccination is a standard vaccination (regular vaccination) for girls/women and boys/men. The dead vaccine contains purified, recombinant L1 proteins from the capsid of the papillomavirus types. Human papillomaviruses (HPV) are responsible for infections of the skin or mucosa. In addition, it has been proven that the virus, especially the high-risk types 16 and 18 … HPV Vaccine
A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height; further: Inspection (viewing). Skin, mucous membranes and oral cavity. Genital region [Symptoms: Bowenoid papulosis – skin infection with human papillomavirus (HPV) in the genital area, which leads to characteristic papular skin lesions; … HPV Infection: Examination
1st order laboratory parameters – obligatory laboratory tests. Human pallioma virus DNA detection (from biopsy material)HPV types are divided into two groups based on their potential to induce malignant genital disease: HIGH RISK types: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68. LOW RISK types: 6, 11, 42, 43, 44 … HPV Infection: Lab Test
Therapeutic target Improvement of symptomatology Therapy recommendations Elimination of the viruses is usually not possible. Optional forms of local therapy/topical therapy: Epigallocatechin gallate* , sinecatechins (10% ointment)/catechins (green tea extracts). Imiquimod (5% cream)* ; approved only for perianal condyloma and not for intraanal infestation [better recurrence rates than surgical intervention]. Podophyllotoxin (0.5%/0.15%)* . Interferon ß, … HPV Infection: Drug Therapy
Surgical ablation of the skin lesions (ablation) is usually the last therapeutic option after other therapeutic options (e.g., topical application of imiquimod or destructive solutions or ointments such as 5-fluorouracil, podophyllotoxin, trichloroacetic acid, silver nitrate) have been exhausted. In ablative therapy are used: Excision (surgical removal): sharp spoons, ablation with surgical scissors (scissor cutting), curettage, … HPV Infection: Surgical Therapy
HPV vaccination is the most important and effective preventive measure against HPV infections. HPV vaccination against the 9 major virus types HPV 6, 11, 16, 18, 31, 33, 45, 52, and 58 (nine-way HPV vaccine) is available for girls and boys between 9 and 14 years of age. The “Standing Commission on Vaccination” (STIKO) recommends … HPV Infection: Prevention
The following symptoms and complaints may indicate human papillomavirus (HPV) infection: Leading symptoms (see disease below) (modified from). Sex of the affected person Disease Associated HPV types ♂ ♀ Bowenoid papulosis – skin infection in the genital area resulting in characteristic papular skin lesions. 16, 18 ♂ ♀ Condylomata acuminata (synonyms: condylomata, wet warts, genital … HPV Infection: Symptoms, Complaints, Signs
Pathogenesis (development of disease) Human papillomaviruses (HPV) are transmitted primarily through sexual contact, but also through other physical contact. Even minimal skin or mucosal lesions (mucosal injuries) are sufficient for the virus to enter the body. After contact with the pathogen, only epithelial cells are infected. This results in growths with the typical clinical picture. … HPV Infection: Causes
Family history (medical history) is an important component in the diagnosis of human papillomavirus (HPV) infections. Family history Social anamnesis Current medical history/systemic medical history (somatic and psychological complaints). In what places have you noticed changes? What do these changes look like? Do you have itching, burning or discharge? Do you have any bleeding? Vegetative … HPV Infection: Medical History
Cardiovascular (I00-I99). Hemorrhoids (esp. with inflammatory change). Marisques – folds of skin on the anus, which usually remain after perianal thrombosis. Skin and subcutaneous (L00-L99). Ectopic sebaceous glands Fibromas Papillomatous pigmented nevus cell nevi Lichen ruber planus (nodular lichen) Nevi (pigment mark, often called “mole” or “birthmark” in common parlance). Seborrheic warts Infectious and parasitic … HPV Infection: Or something else? Differential Diagnosis
The following are the most important conditions or complications that may be contributed to by human papillomavirus (HPV) infections: Certain conditions originating in the perinatal period (P00-P96). Respiratory distress in newborns with laryngeal papillomatosis. Neoplasms – tumor diseases (C00-D48). Anogenital carcinomas Anal carcinoma (anal cancer; 5% of all malignant neoplasms of the gastrointestinal tract; incidence: … HPV Infection: Complications