Medical history (history of illness) represents an important component in the diagnosis of mesangial IgA glomerulonephritis.
Family history
- Is there a history of frequent kidney disease in your family?
Social history
Current medical history/systemic history (somatic and psychological complaints).
- Have you noticed water retention on your body?
- Have you noticed any changes in your urine?
Vegetative anamnesis incl. nutritional anamnesis.
- Have you gained body weight unintentionally? If so, how fast?
- Do you smoke? If yes, how many cigarettes, cigars or pipes per day?
- Do you drink alcohol? If yes, what drink(s) and how many glasses per day?
- Do you use drugs? If yes, what drugs and how often per day or per week?
Self history incl. medication history.
- Pre-existing conditions (renal disease, cardiovascular disease).
- Operations
- Allergies
Medications (nephrotoxic – drugs that damage the kidneys/nephrotoxic drugs).
- ACE inhibitors and AT1- receptor antagonists (drugs used to treat hypertension; side effects – acute: decrease in glomerular filtration rate (GFR), associated with a rise in creatinine: ACE inhibitors as well as AT1-receptor antagonists abolish vasoconstriction (vasoconstriction) in the vas efferens, and a decrease in GFR and a rise in serum creatinine result. Up to 0.1 to 0.3 mg/dl, this is usually tolerable.However, in the presence of hemodynamically relevant renal artery stenosis (not uncommon in patients with atherosclerosis/atherosclerosis/arteriosclerosis), GFR becomes markedly angiotensin II-dependent, and administration of an ACE inhibitor or AT1 receptor antagonist may result in acute renal failure/ANV)!
- Antiphlogistic and antipyretic analgesics (analgesics; nonsteroidal anti-inflammatory drugs (NSAID), nonsteroidal anti-inflammatory drugs) and nonsteroidal anti-inflammatory drugs (NSAIDs), respectively, such as:
- Acetylsalicylic acid (ASA).
- Diclofenac
- Ibuprofen/naproxen
- Indometacin
- Metamizole or novaminsulfone is a pyrazolone derivative and analgesic from the group of non-acidic non-opioid analgesics (highest analgesic and antipyretic activity. Side effects: Circulatory fluctuations, hypersensitivity reactions, and very rarely agranulocytosis.
- Paracetamol
- Phenacetin (phenacetin nephritis)
- Selective COX-2 inhibitors such as rofecoxib, celecoxib (side effects: decreased sodium and water excretion, blood pressure increase and peripheral edema. This is usually accompanied by hyperkalemia (excess potassium)!)
- Antibiotics such as:
- Aminoglycosides such as amikacin, gentamycin (gentamicin), netilmicin, streptomycin, tobramycin, vancomycin.
- Ampicillin (group of β-lactam antibiotics).
- Cephalosporins such as cefuroxime, cefotiam
- Amoxicillin
- Carbenicillin
- Ethambutol (tuberculostat)
- Fenoprofen
- Gyrase inhibitors (extremely rare: acute interstitial nephritis after ciprofloaxin, ofloxacin and norfloxacin).
- Glycopeptide antibiotics such as vancomycin.
- Methicillin (penicillinase-resistant penicillin).
- Oxacillin
- Rifampicin (bactericidal antibiotic from the group of ansamycins).
- Sulfonamdie such as sulfadiazine, cotrimoxazole.
- Antivirals (drugs that inhibit the action of viruses) such as:
- Aciclovir
- Cidofovir
- Foscarnet
- Ganciclovir
- Valaciclovir
- Amphotericin B
- Allopurinol
- Ciclosporin (cyclosporin A)
- Cyclosporin A
- D-Penicillamine
- Gold
- Interferon