Products Emser salt is commercially available as a powder, in the form of lozenges, as a throat spray, nasal drops, as a nasal spray and nasal ointment, among others. These are approved medicinal products and medical devices. The salt has been registered in many countries since 1934. Ems salt comes from a hot thermal spring … Ems Salt
Products MSM is commercially available in the form of tablets, capsules and powder, among others, as a food supplement without indications. It is also applied externally, for example, as a cream and balm. Medicines containing MSM have not yet been approved. Structure and properties MSM (C2H6O2S, Mr = 94.1 g/mol) is a low molecular weight … MSM (Methylsulfonylmethane)
Symptoms Vasomotor rhinitis manifests as a chronic watery-running and/or stuffy nose. Symptoms resemble hay fever but occur year-round and without eye involvement. Both diseases can also occur together. Other possible symptoms include sneezing, itching, headache, frequent swallowing and coughing. Causes and triggers Vasomotor rhinitis is one of the nonallergic and noninfectious rhinitides. The exact causes … Vasomotor Rhinitis
Symptoms Nasal polyps are usually bilateral and localized benign mucosal protrusions of the nasal cavity or sinuses. The leading symptom is nasal constriction leading to a change in voice quality. Other possible symptoms include a watery discharge (rhinorrhea), impaired sense of smell and taste, pain and a feeling of fullness in the head. Nasal polyps … Nasal Polyps
Products Nasal ointments are on sale in many countries from various suppliers. Structure and properties Nasal ointments are semisolid preparations intended for application to the nasal mucosa. They consist of an ointment base such as wool grease, petrolatum, and macrogols. They may contain active pharmaceutical ingredients such as dexpanthenol, antibiotics (mupirocin), sea salt, Emser salt, … Nasal Ointments
Products Nasal sprays are very widely used and there are many different products on the market, which are approved drugs or medical devices (see below). Nasal sprays are also manufactured in pharmacies. Structure and properties Nasal sprays are solutions, emulsions, or suspensions intended for spraying into the nasal cavities. They may contain one or more … Nasal Sprays
Products Astemizole was commercially available in tablet and suspension form (Hismanal). It has been withdrawn from the market in many countries because of potential adverse effects and is no longer available (see below). It may well be replaced by other, better-tolerated antihistamines, such as cetirizine, loratadine, and fexofenadine. Structure and properties Astemizole (C28H31FN4O, Mr = … Astemizole
Products Antihistamines are often taken in the form of tablets. In addition, drops, solutions, lozenges, capsules, gels, creams, eye drops, nasal sprays, and injectable solutions are also available, among others. The first active ingredient from this group was phenbenzamine (Antergan), developed in France in the 1940s. It is no longer commercially available today. Structure and … Antihistamines for Allergies
Effects Antihistamine nasal sprays have antihistamine and antiallergic properties. They are antagonists of histamine at the H1 receptor, reversing histamine effects and thus relieving symptoms such as sneezing, itching, and runny nose. Azelastine is also mast cell stabilizing, which is considered a therapeutic advantage. Glucocorticoid nasal sprays are more effective than antihistamine nasal sprays, but … Antihistamine Nasal Sprays
Products Ciclesonide is administered with a metered-dose inhaler (Alvesco). It has been approved in many countries since 2006. In the United States, it has also been commercially available as a nasal spray for the treatment of allergic rhinitis since 2012 (Zetonna). Structure and properties Ciclesonide (C32H44O7, Mr = 540.7 g/mol) is a prodrug and is … Ciclesonide
Products Fexofenadine is commercially available in tablet form (Telfast, Telfastin Allergo, generic). It was approved in many countries in 1997 and has been available without a doctor’s prescription since 2010. Telfastin Allergo 120 for self-medication went on sale in February 2011. Fexofenadine is the successor product to terfenadine (Teldane), which had to be withdrawn from … Fexofenadine
Anatomical background Humans have 4 sinuses, the maxillary sinuses, the frontal sinuses, the ethmoid sinuses, and the sphenoid sinuses. They are connected to the nasal cavity by 1-3 mm narrow bony openings called ostia and are lined with a thin respiratory epithelium with goblet cells and seromucous glands. The ciliated hairs provide clearance of mucus … Acute Sinusitis