Products Injection preparations are approved as medicinal products. Structure and properties Injection preparations are sterile solutions, emulsions, or suspensions prepared by dissolving, emulsifying, or suspending the active ingredient and excipients in water or a suitable nonaqueous liquid (e.g., fatty oils). Compared with infusions, these are usually small volumes in the range of less than a … Injections
Symptoms Three different main courses can be distinguished: 1. A mild, local reaction manifests as burning, pain, itching, redness of the skin, and formation of a large wheal. The symptoms improve within 4-6 hours. 2. in a moderately severe course, there is a more severe local reaction, with symptoms such as reddening of the skin … Insect Bites
Products Omalizumab is commercially available as a powder and solvent for solution for injection (Xolair). It has been approved in many countries since 2006. Structure and properties Omalizumab is a recombinant, humanized monoclonal antibody with a molecular weight of approximately 149 kDa. Effects Omalizumab (ATC R03DX05) has antiallergic and antiasthmatic properties. The effects are based … Omalizumab
Products Febuxostat is commercially available in the form of film-coated tablets (Adenuric). It was approved in many countries in 2016. It was registered in the EU in 2008 and in the US in 2009 (US: Uloric). Structure and properties Febuxostat (C16H16N2O3S, Mr = 316.4 g/mol), unlike allopurinol, does not have a purine structure. It is … Febuxostat
Products Pegvaliase was approved in the United States in 2018 as an injectable (Palynziq). The drug is not yet registered in many countries. Structure and properties Pegvaliase is a phenylalanine-metabolizing enzyme consisting of recombinant phenylalanine ammonia lyase conjugated to -hydroxysuccinimide methoxy polyethylene glycol. The gene of the enzyme is derived from cyanobacterium . According to … Pegvaliase
Products Penicillins are commercially available today in the form of film-coated tablets, capsules, as solutions for injection and infusion, as powders for preparing an oral suspension, and as syrups, among others. Penicillin was discovered in September 1928 at St. Mary’s Hospital in London by Alexander Fleming. He was working with staphylococcal cultures in Petri dishes. … Penicillins
Products Metamizole is commercially available as drops, tablets, suppositories, and injectables (Minalgin, Novalgin, Novaminsulfon Sintetica, generics). It has been used medicinally since the 1920s. Structure and properties Metamizole (C13H17N3O4S, Mr = 311.4 g/mol) is present in drugs as metamizole sodium. This is the sodium salt and monohydrate of the active ingredient. Metamizole sodium is a … Metamizole: Drug Effects, Side Effects, Dosage and Uses
Allergens are antigens that trigger an unusually strong immune response in a person. The immune response serves to fight a substance perceived as a threat that is normally harmless to the body. This hypersensitivity reaction to allergens is called an allergic reaction. What are allergens? Allergens are antigens that are capable of triggering a type … Allergens: Function & Diseases
Products Pegaspargase is commercially available as an injectable (Oncaspar). The drug was approved in the United States in 2006, in the EU in 2016, and in many countries in 2017. Structure and properties Pegaspargase (PEG-L-asparaginase) is the pegylated enzyme L-asparaginase. The PEG units are covalently attached to the enzyme. Effects Pegaspargase (ATC L01XX24) has antileukemic … Pegaspargases
Products Pegloticase is commercially available as a concentrate for the preparation of an infusion solution (Krystexxa). The drug is not currently registered in many countries. Structure and properties Pegloticase is a recombinant uricase conjugated to mPEG (monomethoxypolyethylene glycol). It is obtained from genetically modified using biotechnological methods. The active ingredient has a molecular weight of … Pegloticase
Products mRNA-1273 enters the market as a white dispersion in multidose containers. It was licensed in the EU on January 6, 2021, and in many countries on January 12, 2021. The vaccine has been studied in a clinical trial involving more than 30,000 participants. The unopened multi-dose vial can be stored at -15 °C to … MRNA-1273
A semen allergy is a rare allergic reaction to male semen. Like any other allergy, it results from sensitization of the immune system to certain proteins in semen. Antihistamines are an acute cure, while desensitization is a possible permanent cure for the allergy. What is a sperm allergy? Although it is very rare, allergic reactions … Sperm Allergy: Causes, Symptoms & Treatment
