Products Bilastin is commercially available in the form of tablets (Bilaxten). It was approved in many countries in 2011. In 2019, an oral solution and melting tablets for children were also registered. Structure and properties Bilastine (C28H37N3O3, Mr = 463.6 g/mol) is a benzimidazole and piperidine derivative. It was developed at FAES Farma in Spain. … Bilastin
Products Atenolol is commercially available in the form of film-coated tablets (Tenormin, generics). It has been approved in many countries since 1976 and is also combined fixed with chlortalidone (Tenoretic). Structure and properties Atenolol (C14H22N2O3, Mr = 266.3 g/mol) is a racemate. It exists as a white powder that is sparingly soluble in water. Effects … Atenolol
Products Ubrogepant was approved in the United States in 2019 in tablet form (Ubrelvy). Structure and properties Ubrogepant (C29H26F3N5O3, Mr = 549.6 g/mol) exists as a white powder that is practically insoluble in water. Effects Ubrogepant has analgesic properties and is effective against other symptoms of migraine such as photophobia (sensitivity to light), phonophobia (sensitivity … Ubrogepant
Symptoms Nausea is an unpleasant and painless sensation that can lead to vomiting. Vomiting is an autonomic response of the body in which the stomach contents are expelled through the mouth with contraction of the muscles. Its primary purpose is to protect the body from toxic and inedible foods and harmful substances. Nausea may be … Nausea and Vomiting
Products Brexpiprazole was approved in the United States in 2015 and in the EU and many countries in 2018 in film-coated tablet form (Rexulti). Structure and properties Brexpiprazole (C25H27N3O2S, Mr = 433.6 g/mol) is structurally closely related to aripiprazole (Abilify, generics). Effects Brexpiprazole (ATC N05AX16) has antipsychotic properties. The effects are due to partial agonism … Brexpiprazole
Products Rolapitant was approved in the form of film-coated tablets in the United States in 2015, in the EU in 2017, and in many countries in 2018 (Varuby). Structure and properties Rolapitant (C25H26F6N2O2, Mr = 500.5 g/mol) is present in the drug as rolapitane hydrochloride, a white powder that is more soluble in water at … Rolapitant
Products Rocuronium bromide is commercially available as a solution for injection (esmeron, generic). It was approved in the United States in 1994 and in many countries in 1995. Structure and properties Rocuronium bromide (C32H53BrN2O4, Mr = 609.7 g/mol) exists as a nearly white to pale yellow, slightly hygroscopic powder that is readily soluble in water. … Rocuronium Bromide
Products Desfesoterodine was approved in many countries in 2019 in sustained-release tablet form (generic, tovedeso). Structure and properties Desfesoterodine (C22H31NO2, Mr = 341.5 g/mol) is the active metabolite of the prodrug fesoterodine as well as tolterodine (detrusitol). It is also referred to as 5-hydroxymethyltolterodine. In the drug, it is present as desfesoterodine succinate. Effects Desfesoterodine … Desfesoterodine
Products Desloratadine is commercially available as 5 mg film-coated tablets and as a solution (Aerius, generics). It has been approved in many countries since 2001. The syrup was replaced in 2011 by a solution that is sugar- and dye-free. The concentration remains identical (0.5 mg/ml). The fixed combination with pseudoephedrine is not yet available in … Desloratadine
Products Levomepromazine is commercially available as film-coated tablets and oral solution (Nozinan). It has been approved in many countries since 1958. Structure and properties Levomepromazine (C19H24N2OS, Mr = 328.5 g/mol) is present in the drugs as levomepromazine hydrochloride or levomepromazine maleate. These are faint yellowish crystalline powders. Levomepromazine maleate is sparingly soluble in water and … Levomepromazine
Products Aripiprazole is commercially available in tablet, meltable tablet, syrup, solution for injection, and sustained-release injection suspension forms (Abilify, Abilify Maintena, generics). It has been approved in many countries since 2004 and in the United States since 2002. Generics entered the market in 2015. Also used is the prodrug aripiprazollauroxil (Aristada). Structure and properties Aripiprazole … Aripiprazole
Products Aripiprazollauroxil was newly approved in the United States in 2015 as a suspension for injection (Aristada). It has not yet been registered in many countries. Structure and properties Aripiprazollauroxil (C36H51Cl2N3O4, Mr = 660.7 g/mol) is the ester of -hydroxymethyl aripiprazole and lauric acid. Aripiprazollauroxil is a prodrug of aripiprazole (Abilify, generic). Unlike oral aripiprazole, … Aripiprazollauroxil
