antiallergic

Prednisolone: Drug Effects, Side Effects, Dosage and Uses

Products Prednisolone is commercially available as tablets, eye drops, eye ointment, cream, ointment, solution, foam, and suppositories (Pred Forte, Prednisolone Streuli, Premandol, Spiricort, Ultracortenol). Structure and properties Prednisone (C21H26O5, Mr = 358.434 g/mol) is the prodrug of prednisolone. Effects Prednisolone (ATC H02AB06) has anti-inflammatory, antiallergic, and immunosuppressive properties. Indications Inflammatory non-infectious skin diseases see under … Prednisolone: Drug Effects, Side Effects, Dosage and Uses

Prednisolone Eye Drops

Products Prednisolone commercially available as an eye drop suspension (Pred forte). Structure and properties Prednisolone is present in the drug in the form of the ester prednisolone acetate (C23H30O6, Mr = 402.5 g/mol). Prednisolone acetate is a prodrug that is hydrolyzed in the body to the active metabolite prednisolone. Effects Prednisolone acetate (ATC S01BA04) has … Prednisolone Eye Drops

Prednisone

Products Prednisone is available in tablet form from several manufacturers (Prednisone Galepharm, Prednisone Axapharm, Prednisone Streuli). Lodotra sustained-release tablets were approved in 2011. Structure and properties Prednisone (C21H26O5, Mr = 358.4 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug of prednisolone. Effects Prednisolone (ATC A07EA03, ATC … Prednisone

Dimetinden Maleate Drops

Products Dimetinden maleate is available as oral drops (Feniallerg drops). They were formerly called Fenistil drops. The drug has been approved in many countries since 1961. Structure and properties Dimetindene (C20H24N2, Mr = 292.4 g/mol) is present in drugs as dimetindene maleate, a white crystalline powder that is poorly soluble in water. The name is … Dimetinden Maleate Drops

Dimetindenmaleate

Products Dimetinden maleate is commercially available as drops, gel, lotion, nasal spray, and nasal drops (Fenistil, Feniallerg, Vibrocil, Otriduo). The nasal products also contain the vasoconstrictor phenylephrine. The Fenistil products used internally (systemically) were renamed Feniallerg in 2009. The capsules and dragées are no longer available. Structure and properties Dimetind (C20H24N2, Mr = 292.4 g/mol) … Dimetindenmaleate

Dimetinden Maleate Gel

Products Dimetinden maleate has been commercially available in many countries since 1974 in the form of a gel (Fenistil Gel). Structure and properties Dimetindene (C20H24N2, Mr = 292.4 g/mol) is present in drugs as dimetindene maleate, a white crystalline powder that is poorly soluble in water. The name is derived from the two methyl groups … Dimetinden Maleate Gel

Olopatadine

Products Olopatadine is commercially available in the form of eye drops (Opatanol). It has been approved in many countries since 2003. Structure and properties Olopatadine (C21H23NO3, Mr = 337.41 g/mol) is present in drugs as olopatadine hydrochloride. It is a dihydrodibenzoxepin derivative with a tricyclic structure. Effects Olopatadine (ATC S01GX09) has antihistamine, antiallergic, and mast … Olopatadine

Omalizumab

Products Omalizumab is commercially available as a powder and solvent for solution for injection (Xolair). It has been approved in many countries since 2006. Structure and properties Omalizumab is a recombinant, humanized monoclonal antibody with a molecular weight of approximately 149 kDa. Effects Omalizumab (ATC R03DX05) has antiallergic and antiasthmatic properties. The effects are based … Omalizumab

Ketotifen

Products Ketotifen is commercially available in tablet form and as eye drops (Zaditen, Zabak). It has been approved in many countries since 1977. See also under ketotifen eye drops. Structure and properties Ketotifen (C19H19NOS, Mr = 309.43 g/mol) is a tricyclic benzocycloheptathiophene derivative structurally related to pizotifen (Mosegor, out of commerce). It is present in … Ketotifen

Ketotifen Eye Drops

Products Ketotifen eye drops have been approved in many countries since 2000 (Zaditen Ophtha / -SDU, Zabak). Structure and properties Ketotifen (C19H19NOS, Mr = 309.43 g/mol) is a tricyclic benzocycloheptathiophene derivative structurally related to pizotifen (Mosegor, out of commerce). It is present in drugs as ketotifen hydrogen fumarate, a white to brownish yellow crystalline powder … Ketotifen Eye Drops

Hydrocortisone Soft Ointment

Products and production Hydrocortisone soft ointments are manufactured in 1% or 2% concentrations in pharmacies as extemporaneous preparations. Concentration: 1% 2% Hydrocortisone acetate 1.0 2.0 Soft ointment KA or Unguentum Cordes 99.0 98.0 Recipe DMS The soft ointment consists mostly of viscous kerosene and petrolatum. The manufacturing prescription can be found in the DMS. Effects … Hydrocortisone Soft Ointment

Hydrocortisone Acetate

Products To date, hydrocortisone acetate is the only glucocorticoid approved for self-medication in many countries and is available without a doctor’s prescription. A cream (Dermacalm with dexpanthenol) and a hydrocream (Sanadermil) are available. Hydrocortisone was the first dermocorticoid and was introduced in the 1950s. Structure and properties Hydrocortisone acetate (C23H32O6, Mr = 404.5 g/mol) is … Hydrocortisone Acetate