Effects Reverse transcriptase inhibitors (ATC J05AF) have antiviral properties against HIV. The effects are due to inhibition of the viral enzyme reverse transcriptase, which transcribes viral RNA into DNA and is important for viral replication. Structure and properties Within the drug group, two distinct classes are distinguished. The so-called nucleoside reverse transcriptase inhibitors, abbreviated NRTIs, … Reverse Transcriptase Inhibitors (HIV)
Effects Fusion inhibitors have antiviral properties against viruses. They inhibit fusion with the host cell and prevent virus entry. Indications For the treatment of viral infectious diseases. Active ingredients Enfuvirtide (Fuzeon) Umifenovir (Arbidol)
Products Paritaprevir was approved in many countries in 2014 in film-coated tablet form (Viekirax, combination drug). Effects Paritaprevir has antiviral properties against HCV. The effects are due to binding to the NS3/4A protease complex. HCV NS3 serine protease is an enzyme involved in viral replication. To increase availability and allow once-daily administration, paritaprevir is combined … Paritaprevir
Products Neuraminidase inhibitors are commercially available in the form of capsules, powder for oral suspension, powder inhalers, and injectables. The first agents to be approved were zanamivir (Relenza) in 1999, followed by oseltamivir (Tamiflu). Laninamivir (Inavir) was released in Japan in 2010 and Peramivir (Rapivab) in the USA in 2014. The public is most familiar … Neuraminidase Inhibitor
Products Melissa is available as an open product or in the form of tea bags in pharmacies and drugstores. Medicines containing lemon balm, extracts and the essential oil are on the market in the form of dragées, drops and capsules, among others, usually in combination with other medicinal plants. Stem plant Melissa L. of the … Melissa: Medicinal Uses
Products Abacavir is commercially available as film-coated tablets and as an oral solution (Ziagen, combination products). It has been approved in many countries since 1999. Generic versions are approved. Structure and properties Abacavir (C14H18N6O, Mr = 286.3 g/mol) is present in drugs, among other forms, as abacavir sulfate, a white crystalline powder that is soluble … Abacavir
Products Lysine is commercially available as a monopreparation from Burgerstein, among others, in the form of tablets. Structure and properties Lysine (C6H14N2O2, Mr = 146.2 g/mol) is a natural and essential amino acid found in proteins and, for example, in meat. Essential means that the body must take it in with food and does not … Lysine
Products Lysozyme is mainly commercialized in medicines for sore throat, e.g., Lysopain and Sangerol. Structure and properties Lysozyme is an endogenous mucopolysaccharidase (protein, enzyme) found in saliva and elsewhere. It is composed of 129 amino acids. Effects Lysozyme (ATC A01AB11) has bactericidal, antiviral, and anti-inflammatory properties. Indications Acute inflammatory conditions of the mouth and throat, … Lysozyme
Products Sofosbuvir is commercially available in the form of film-coated tablets (Sovaldi). It was approved in the United States and EU in 2013 and in many countries in 2014. The very high price of the drug has been a source of debate. Sofosbuvir is also combined fixed with ledipasvir (Harvoni). Cheaper generics are available in … Sofosbuvir
Products Preparations from celandine are commercially available as tinctures (drops), among others. The medicinal drug is available in pharmacies and drugstores. Celandine is also called “Chelidonium” because of the generic name. Stem plant Celandine L. from the poppy family (Papaveraceae) is also native to Europe. What is special about the plant is the yellow-orange milky … Celandine: Medicinal Uses
Products Propolis is contained in ointments, creams, tinctures, oral sprays, lip balms, capsules and body care products, among others. As a rule, these are not registered drugs, but cosmetics. The pure substance is available from beekeepers or in pharmacies and drugstores. When buying propolis products, care must be taken to ensure that the substance is … Propolis (Bee Glue): Effects and Health Benefits
Products Amantadine is commercially available as film-coated tablets, capsules, and an infusion solution (Symmetrel, PK-Merz). It has been approved in many countries since 1966. Structure and properties Amantadine (C10H17N, Mr = 151.2 g/mol) is present in drugs as amantadine sulfate or amantadine hydrochloride. Amantadine hydrochloride is a white crystalline powder that is readily soluble in … Amantadine
