Products Pholedrin is no longer available as a drug in many countries. It was formerly contained in Ortho-Maren capsules, among other products. Structure and properties Pholedrine (C9H13NO, Mr = 151.2 g/mol) Effects Pholedrine (ATC C01CA30) has sympathomimetic properties. Indications Orthostatic hypotensive circulatory complaints and circulatory dysregulation.
Products Silodosin has been approved in hard capsule form in the United States since 2008, in the EU since 2010, and in many countries since 2016 (Urorec). Generic versions are registered in some countries. Structure and properties Silodosin (C25H32F3N3O4, Mr = 495.5) exists as a white to yellowish powder that is sparingly soluble in water. … Silodosin
Products Simeprevir was approved in capsule form in the United States in 2013, in the EU in 2014, and in many countries in 2015 (Olysio). Structure and properties Simeprevir (C38H47N5O7S2, Mr = 749.9 g/mol) is present in the drug product as simeprevir sodium. The macrocyclic molecule contains a sulfonamide moiety, which may cause adverse effects … Simeprevir
Products Flecainide is commercially available as tablets and as a solution for injection (Tambocor). It has been approved in many countries since 1984. Structure and properties Flecainide (C17H20F6N2O3, Mr = 414.3 g/mol) is present in drugs as flecainide acetate, a white, crystalline, and very hygroscopic powder that is soluble in water. It is an amide-type … Flecainide
Products Articaine is marketed as a solution for injection and exclusively in combinations with epinephrine. It has been approved in many countries since 1976. Structure and properties Articaine (C13H20N2O3S, Mr = 284.4 g/mol) is present in drugs as articaine hydrochloride, a racemate and white crystalline powder that is readily soluble in water. Effects Articaine (ATC … Articaine
Products Afatinib was approved in the US and EU in 2013 and in many countries in 2014 in film-coated tablet form (Giotrif). Structure and properties Afatinib (C24H25ClFN5O3, Mr = 485.9 g/mol) is a 4-aniline quinazoline derivative that is present in drugs as afatinib dimaleate, a white to brownish-yellow powder that is soluble in water. It … Afatinib
Products Delafloxacin was approved in the United States in 2017, in the EU in 2019, and in many countries in 2020 as a powder for a concentrate for solution for infusion and in tablet form (Quofenix). Structure and properties Delafloxacin (C18H12ClF3N4O4, Mr = 440.8 g/mol) belongs to the group of fluoroquinolones. It is present in … Delafloxacin
Products Oxymorphone is commercially available in the United States as tablets and sustained-release tablets and has also been administered parenterally and rectally. It is not registered in many countries. Oxymorphone has been approved in the U.S. since 1959 (brand names: Numorphan, Opana, Opana ER, generics). It is a narcotic drug. Due to the potential for … Oxymorphone
Products Dembrexin is commercially available as a powder for administration with feed as a veterinary drug. It has been approved in many countries since 1988. Structure and properties Dembrexin (C13H17Br2NO2, Mr = 379.1 g/mol) is a benzylamine. It is structurally closely related to bromhexine (e.g., bisolvone) and ambroxol (e.g., mucosolvone) and is present in the … Dembrexin
