Products Dihydrocodeine is commercially available as sustained-release tablets, drops, and syrup (Codicontin, Paracodin, Escotussin, Macatussin Syrup). It has been approved in many countries since 1957. Structure and properties Dihydrocodeine (C18H23NO3, Mr = 301.4 g/mol) is a hydrogenated derivative of codeine. It is present in drugs as dihydrocodeine thiocyanate, dihydrocodeine hydrochloride, or dihydrocodeine tartrate. Dihydrocodeine tartrate … Dihydrocodeine
Products Melphalan is commercially available in the form of film-coated tablets and as an injection/infusion preparation (Alkeran). It has been approved in many countries since 1964. Structure and properties Melphalan (C13H18Cl2N2O2, Mr = 305.2 g/mol) is a phenylalanine derivative of nitrogen-lost. It is practically insoluble in water. It exists as a pure L-enantiomer. The racemate … Melphalan
Products Carmustine is commercially available in many countries as a powder and solvent for the preparation of an infusion solution (BiCNU). An implant is also available in some countries (Gliadel). Structure and properties Carmustine (C5H9Cl2N3O2, Mr = 214.0 g/mol) belongs to the nitrosoureas. It exists as a yellowish, granular powder that is very sparingly soluble … Carmustine
Products Caffeine citrate solution was newly approved in many countries in 2016 (Peyona). It was available earlier in other countries. Structure and properties Caffeine (C8H10N4O2, Mr = 194.2 g/mol) exists as a white crystalline powder or as white silk-like crystals and is sparingly soluble in water. The substance sublimes readily. Citric acid monohydrate (C6H8O7 – … Caffeine Citrate Solution
Varenicline helps smokers quit smoking Quitting smoking presents an immense challenge to those affected. The chances of withdrawal success can be increased by nicotine replacement products such as patches or chewing gum. If these attempts fail, a possible alternative is therapy with varenicline. The drug has been tried and tested, and its positive effect on … Varenicline for Smoking Cessation
Products Metformin is commercially available in many countries in the form of film-coated tablets and has been available since 1960. In addition to the original Glucophage, numerous generics are available today. Metformin is often combined with various other antidiabetic drugs fix. It has been used medically since 1957. Other antidiabetic biguanides such as phenformin and … Metformin: Drug Effects, Side Effects, Dosage and Uses
Products Glycopyrronium bromide is commercially available in the form of hard capsules with a powder for inhalation (Seebri Breezhaler). It was approved in the EU in 2012 and in many countries in April 2013. Glycopyrronium bromide is also combined fixed with indacaterol (Ultibro Breezhaler, approved in many countries in 2014). In 2020, a combination of … Glycopyrronium Bromide
Pramipexole belongs to the dopamine antagonists. The drug is used to treat Parkinson’s disease. What is pramipexole? Pramipexole belongs to the dopamine antagonists. The drug is used to treat Parkinson’s disease. Pramipexole is a drug from the group of dopamine antagonists. This means that the substance mimics the effect of natural dopamine. The drug is … Pramipexole: Effects, Usage & Risks
Products Cimetidine was commercially available in the form of film-coated tablets (Tagamet). Currently, there are no longer any human medicines registered with the active ingredient in many countries. Cimetidine was developed in the 1960s and 1970s under the leadership of Sir James Black as the first wirsktoff from the group of H2 receptor antagonists and … Cimetidine
Products Albendazole is commercially available as chewable tablets and as a suspension (zentel). It was approved in many countries in 1993. Structure and properties Albendazole (C12H15N3O2S, Mr = 265.3 g/mol) exists as a white to slightly yellowish powder that is practically insoluble in water. It is a benzimidazole derivative and is completely biotransformed after absorption. … Albendazole
Products Nicomorphine was commercially available in the form of tablets, suppositories, and as a solution for injection (Vilan). It had been approved in many countries since 1957. It was discontinued in 2015. Structure and properties Nicomorphine (C29H25N3O5, Mr = 495.5 g/mol), like heroin, is an ester as well as a nicotinic acid derivative of morphine … Nicomorphine
Products Urapidil is commercially available as a solution for injection (Ebrantil). It has been approved in many countries since 1983. Structure and properties Urapidil (C20H29N5O3, Mr = 387.5 g/mol) is a derivative of uracil and piperazine. It is present in drugs as urapidil hydrochloride. Effects Urapidil (ATC C02CA06) has antihypertensive and sympatholytic properties. It lowers … Urapidil
