Products Asenapine is commercially available in the form of sublingual tablets (Sycrest). It was approved in many countries in 2012. In the United States, it has been registered since 2009. Structure and properties Asenapine (C17H16ClNO, Mr = 285.8 g/mol) is present in the drug as asenapine maleate. It belongs to the class of dibenzooxepin pyrroles. … Asenapine
Products The first active ingredient in the quinolone group to be introduced was nalidixic acid in 1967 (NegGram). It is no longer commercially available in many countries. Other drugs are available today (see below). Various dosage forms are available, for example, film-coated tablets, oral suspensions, eye drops, ear drops, and infusion solutions. Due to adverse … Quinolone
Products Duloxetine is commercially available in the form of capsules (Cymbalta, generic). It has been approved in many countries since 2005. Structure and properties Duloxetine (C18H19NOS, Mr = 297.4 g/mol) is present in drugs as pure -duloxetine hydrochloride, a white to light brown powder that is sparingly soluble in water. Effects Duloxetine (ATC N06AX21) has … Duloxetine
Products Agomelatine is commercially available in the form of film-coated tablets (Valdoxan, generic). It was approved in the EU in 2009 and in many countries in 2010. Structure and properties Agomelatine (C15H17NO2, Mr = 243.30 g/mol) exists as a white powder that is practically insoluble in water. It is a naphthalene analog of the epiphyseal … Agomelatine
Products Propranolol is commercially available in tablet, sustained-release capsule, and solution forms (Inderal, generic, hemangiol). It has been approved in many countries since 1965. Structure and properties Propranolol (C16H21NO2, 259.34 g/mol) is present in drugs as propranolol hydrochloride, a white powder that is soluble in water. Propranolol is a racemate. The -enantiomer is predominantly active. … Propranolol
Products Nicotine is commercially available in the form of chewing gum, lozenges, sublingual tablets, transdermal patch, oral spray, and inhaler (Nicorette, Nicotinell, generics). The first nicotine replacement product was approved in many countries in 1978. Structure and properties Nicotine (C10H14N2, Mr = 162.2 g/mol) exists as a colorless to brownish, viscous, hygroscopic, volatile liquid that … Nicotine: Drug Effects, Side Effects, Dosage and Uses
Products Tizanidine is commercially available in tablet and sustained-release capsule form (Sirdalud, Sirdalud MR, generics). It has been approved in many countries since 1983. Structure and properties Tizanidine (C9H8ClN5S, Mr = 253.7 g/mol) is present in drugs as tizanidine hydrochloride, a white crystalline powder that is somewhat soluble in water. It is an imidazoline and … Tizanidin
Products Ulipristal acetate was approved in the EU in 2009 and in the United States in 2010 (ellaOne, film-coated tablets). In many countries, ulipristal acetate was registered in late 2012. Since February 1, 2016, the morning-after pill has been available in pharmacies without a doctor’s prescription after a consultation and dispensing documentation (see also under … Ulipristal Acetate
Products Palonosetron is commercially available as a solution for injection and as soft capsules (Aloxi, generic). It has been approved in many countries since 2006. The capsules were registered in 2013. Also approved is a fixed combination of netupitant and palonosetron in capsule form; see netupitant palonosetron. Structure and properties Palonosetron (C19H24N2O, Mr = 296.4 … Palonosetron
Products Tasimelteon was approved in the United States in 2014 and in the EU in 2015 in capsule form (Hetlioz). The drug is not currently registered in many countries. Structure and properties Tasimelteon (C15H19NO2, Mr = 245.3 g/mol) exists as a white crystalline powder that is sparingly soluble in water. It is structurally related to … Tasimelteon
Products Cinacalcet is commercially available in the form of film-coated tablets (Mimpara, some countries: Sensipar). It has been approved in many countries since 2004. Generic versions were registered in 2016. Structure and properties Cinacalcet (C22H22F3N, Mr = 357.4 g/mol) is present in drugs as cinacalcet hydrochloride, a white crystalline powder that is sparingly soluble in … Cinacalcet
Products Ciprofloxacin is commercially available as film-coated tablets, oral suspension, infusion preparation, eye drops, eye ointment (Ciloxan), and ear drops (Ciproxin HC + hydrocortisone). In addition to the original Ciproxin, various generics are available. Ciprofloxacin was approved in many countries in 1987. This article refers to peroral administration. Structure and Properties Ciprofloxacin (C17H18FN3O3, Mr = … Ciprofloxacin
