cyp2d6

Risperidone: Drug Effects, Side Effects, Dosage and Uses

Products Risperidone is commercially available as film-coated tablets, meltable tablets, an oral solution, and a suspension for intramuscular administration (Risperdal, generics). The active ingredient has been approved in many countries since 1994. Structure and properties Risperidone (C23H27FN4O2, Mr = 410.5 g/mol) exists as a white powder that is practically insoluble in water. It is a … Risperidone: Drug Effects, Side Effects, Dosage and Uses

Ritonavir

Products Ritonavir is commercially available as a monopreparation in the form of film-coated tablets (Norvir). It was approved in many countries, in the United States and in the EU in 1996, and is also used as a pharmacokinetic booster in combination with antiviral agents (eg, lopinavir). Norvir syrup is no longer marketed in many countries. … Ritonavir

Dihydrocodeine

Products Dihydrocodeine is commercially available as sustained-release tablets, drops, and syrup (Codicontin, Paracodin, Escotussin, Macatussin Syrup). It has been approved in many countries since 1957. Structure and properties Dihydrocodeine (C18H23NO3, Mr = 301.4 g/mol) is a hydrogenated derivative of codeine. It is present in drugs as dihydrocodeine thiocyanate, dihydrocodeine hydrochloride, or dihydrocodeine tartrate. Dihydrocodeine tartrate … Dihydrocodeine

Mirabegron

Products Mirabegron is commercially available in the form of sustained-release film-coated tablets (Betmiga, USA: Myrbetriq). It was approved in the US and EU in 2012 and in many countries in 2014. Mirabegron was the first agent from the beta3 agonist group to be approved for the treatment of irritable bladder. It was originally intended to … Mirabegron

Mirtazapine: Drug Effects, Side Effects, Dosage and Uses

Products Mirtazapine is commercially available in the form of film-coated tablets and meltable tablets (Remeron, generics). It has been approved in many countries since 1999. Structure and properties Mirtazapine (C17H19N3, Mr = 265.35 g/mol) is a racemate and exists as a white crystalline powder that is sparingly soluble in water. It is structurally closely related … Mirtazapine: Drug Effects, Side Effects, Dosage and Uses

Abiraterone Acetate

Products Abiraterone is commercially available in the form of film-coated tablets (Zytiga). It has been approved in many countries since 2011. Structure and properties Abiraterone acetate (C26H33NO2, Mr = 391.5 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug and is rapidly biotransformed in the body to … Abiraterone Acetate

Paroxetine

Products Paroxetine is commercially available as film-coated tablets and as a suspension (Deroxat, generic). It has been approved in many countries since 1993. Paroxetine is also marketed as Seroxat and Paxil in some countries. Slow-release paroxetine (CR) is not currently available in many countries. Structure and properties Paroxetine (C19H20FNO3, Mr = 329.4 g/mol) is present … Paroxetine

Dextromethorphan

Products Dextromethorphan is available in the form of tablets, lozenges, sustained-release capsules, syrup, and drops, among others (in many countries, for example, Bexin, Calmerphan, Calmesin, Pulmofor, combination preparations). The first drugs came on the market in the 1950s. Structure and properties Dextromethorphan (C18H25NO, Mr = 271.4 g/mol) was developed as an analog of codeine and … Dextromethorphan

Cariprazine

Products Cariprazine was approved in the United States in 2015 and in many countries and the EU in 2018 in capsule form (Reagila, some countries: Vraylar). Structure and properties Cariprazine (C21H32Cl2N4O, Mr = 427.4 g/mol) is a piperazine and dimethylurea derivative. It is present in the drug as cariprazine hydrochloride, a white powder. Active metabolites … Cariprazine

Carteolol

Products Carteolol is available in the form of extended-release eye drops (Arteoptic LA). Carteolol has been approved in many countries since 1984. Arteopilo, the combination with pilocarpine, is no longer marketed in many countries. Structure and properties Carteolol (C16H24N2O3, Mr = 292.4 g/mol) is a dihydroquinolinone and a racemate. It is present in drugs as … Carteolol

Carvedilol

Products Carvedilol is commercially available in tablet form (Dilatrend, generic). It has been approved in many countries since 1995. Carvedilol is also combined with ivabradine fixed (Carivalan). Structure and properties Carvedilol (C24H26N2O4, Mr = 406.5 g/mol) is a racemate, with both enantiomers participating in the pharmacological effects. It exists as a white crystalline powder that … Carvedilol

Thioridazine

Products Thioridazine has been off the market in many countries since 2005 because of cardiac risks. Melleril and Mellerette tablets are out of commerce. In Germany and other countries, thioridazine remains on the market. Structure and properties Thioridazine (C21H26N2S2, Mr = 370.6 g/mol) is a phenothiazine derivative with a piperidinyl alkyl side chain. In drugs, … Thioridazine