cyp450 inhibitors

Efinaconazole

Products Efinaconazole is commercially available in the United States in the form of a solution (Jublia). The active ingredient has not yet been registered in many countries. Structure and properties Efinaconazole (C18H22F2N4O, Mr = 348.4 g/mol) structurally belongs to the triazole antifungals. Effects Efinaconazole has antifungal properties. The effects are due to inhibition of lanosterol … Efinaconazole

Venetoclax

Products Venetoclax was approved in the US and EU in 2016 and in many countries in 2018 in film-coated tablet form (Venclyxto, Venclexta). Structure and properties Venetoclax (C45H50ClN7O7S, Mr = 868.4 g/mol) exists as a light to dark yellow powder that is sparingly soluble in water. Effects Venetoclax (ATC L01XX52) has antitumor and cytotoxic properties. … Venetoclax