Products Chewing gums with active pharmaceutical ingredients are available in pharmacies and drugstores. In many countries, only a few pharmaceuticals are approved as chewing gums. Most belong to other product categories, for example, confectionery, dietary supplements, or dental care products. Structure and properties Active ingredient-containing chewing gums are solid single-dose preparations with a base mass … Chewing Gums
Products Amoxicillin is commercially available in the form of tablets, film-coated tablets, dispersible tablets, as powder or granules for the preparation of a suspension, as an infusion and injection preparation, and as a veterinary drug. In addition to the original Clamoxyl, numerous generics are available today. Amoxicillin was launched in 1972 and has been approved … Amoxicillin (Amoxil)
Products Antibiotics (singular: antibiotic) are commercially available in the form of tablets, dispersible tablets, capsules, as infusion preparations, suspensions and syrups for children, and as granules, among others. There are also some topical preparations, such as creams, ointments, eye drops, eye ointments, ear drops, nasal ointments and sore throat tablets. The first active ingredient from … Antibiotics: Antibacterial Drugs
Products Antiepileptic drugs are commercially available in the form of tablets, dispersible tablets, capsules, solutions, suspensions, syrups, as nasal sprays, enemas, and as injectables, among others. Structure and properties The antiepileptic drugs are structurally heterogeneous agents. Within the class, several groups can be identified (see below). Effects The agents have antiepileptic, anticonvulsant, and muscle relaxant … Antiepileptic Drugs
Definition Onset of action is the time at which the effect of a drug becomes observable or measurable. There is a delay between the administration of the drug (application) and the onset of action. We refer to this period of time as the latency period. It is in the range of minutes, hours, days, or … Onset of Action
Products Fluoxetine is commercially available as tablets, dispersible tablets, and capsules (Fluctine, generics, USA: Prozac). It has been approved in many countries since 1991. Structure and properties Fluoxetine (C17H18F3NO, Mr = 309.3 g/mol) is present in the drugs as fluoxetine hydrochloride, a white crystalline powder that is sparingly soluble in water. It is a racemate … Fluoxetine: Drug Effects, Side Effects, Dosage and Uses
Products Bosentan is commercially available in the form of tablets and dispersible tablets (Tracleer). It has been approved in many countries since 2002. Generic versions were registered in 2017. Structure and properties Bosentan (C27H29N5O6S, Mr = 551.6 g/mol) is present in drugs as bosentan monohydrate, a white to yellowish powder that is poorly soluble in … Bosentan
Definition and properties Dispersible tablets are uncoated tablets or film-coated tablets that can be suspended or dissolved in water before ingestion. They are designated by the Pharmacopoeia as “tablets for the preparation of a suspension for ingestion” and “tablets for the preparation of a solution for ingestion.” When dissolved, a homogeneous suspension or solution is … Dispersible Tablets
Definition After a drug is ingested, it passes through the esophagus into the stomach and into the small intestine. There, the active ingredient must first be released from the dosage form. This is the prerequisite for it to be absorbed into the bloodstream via the cells of the mucosa. The dosage form thus exerts a … Release (Liberation)
Products Mood stabilizers are commercially available in the form of tablets, dispersible tablets, and solutions, among others. The best-known active ingredient in this group is lithium. Structure and properties Mood stabilizers are organic molecules (antiepileptic drugs) and salts (lithium). Effects The agents have mood-stabilizing properties, meaning that they are active against depressive and manic episodes, … Mood Stabilizer
Products Lamotrigine is commercially available as tablets and dispersible or chewable tablets (Lamictal, generics). It has been approved in many countries since 1994. Vanillin is typically added to the tablets as a flavoring agent and saccharin as a sweetener. Structure and properties Lamotrigine (C9H7Cl2N5, Mr = 256.1 g/mol) is a chlorinated phenyltriazine derivative that was … Lamotrigine (Lamictal)
Products Artemether is commercially available as tablets and dispersible tablets as a fixed combination with lumefantrine (Riamet, some countries: Coartem). It has been approved in many countries since 1999. Structure and properties Artemether (C16H26O5, Mr = 298.4 g/mol) is a methyl ether dervate of the sesquiterpene artemisinin from the annual mugwort (, Qing Hao), a … Artemether