Definition and properties When we take a tablet or capsule, it contains a defined amount of an active pharmaceutical ingredient. Usually, the full dose does not enter the bloodstream. Some active ingredients are not fully released from the dosage form (liberation), others are only partially absorbed from the intestine (absorption), and some are metabolized in … Bioavailability
Products Mebendazole is commercially available in the form of tablets (Vermox). It has been approved in many countries since 1974. Structure and properties Mebendazole (C15H13N3O3, Mr = 295.3 g/mol) is a benzimidazole derivative and a carbamate. It exists as a white powder that is practically insoluble in water. Effects Mebendazole (ATC P02CA01) has antihelminthic properties. … Mebendazole
Products and production Morphine drops are an aqueous dropping solution of morphine hydrochloride, usually in concentration 1% or 2%, maximum 4%. The concentration refers to the salt; the effective amount of morphine base is less. The drug is subject to strict control as an anesthetic and is available only on prescription. The morphine drops of … Morphine Drops
Products Levodopa for inhalation was approved in the United States in 2018 and in the EU in 2019 (Inbrija, capsules containing a powder for inhalation). Structure and properties Levodopa (C9H11NO4, Mr = 197.2 g/mol) exists as a white crystalline powder that is sparingly soluble in water. It is a derivative of the amino acid tyrosine. … Levodopa Inhalation
Products Oxybutynin is commercially available in tablet form and as a transdermal patch (Ditropan, Kentera). It has been approved in many countries since 1988, and the transdermal patch has been available since 2007. Extemporaneous formulations are also produced; see Intravesical oxybutynin solution (for use in the urinary bladder). Other dosage forms have been released in … Oxybutynin
Products The fixed combination Targin with the active ingredients oxycodone and naloxone was approved in many countries in 2009. In other countries, the drug is also known as Targinact or Targiniq. In 2016, generic versions were approved in many countries. They went on sale in 2018. Structure and properties Oxycodone (C18H21NO4, Mr = 315.4 g/mol) … Oxycodone, Naloxone
Products Naltrexone is commercially available in the form of film-coated tablets (naltrexin). It has been approved in many countries since 2003. Structure and properties Naltrexone (C20H23NO4, Mr = 341.40 g/mol) is a synthetically produced opioid related to oxymorphone. It is present in drugs as naltrexone hydrochloride, a white, hygroscopic powder that is readily soluble in … Naltrexone
Products Budesonide is commercially available as a monopreparation for inhalation as a powder inhaler and suspension (Pulmicort, generics). It is also combined fixed with formoterol (Symbicort Turbuhaler, Vannair Dosage Aerosol). This article refers to monotherapy. Budesonide has been approved in many countries since 1988. Structure and properties Budesonide (C25H34O6, Mr = 430.5 g/mol) is a … Budesonide (Inhalation)
Products Budesonide nasal sprays have been approved in many countries since 1995 (Cortinasal, generic). Rhinocort nasal spray has not been marketed since 2018. Sales of the Rhinocort turbuhaler were discontinued in 2020. Structure and properties Budesonide (C25H34O6, Mr = 430.5 g/mol) is a racemate and exists as a white, crystalline, odorless, tasteless powder that is … Budesonide Nasal Spray
Products Budesonide sustained-release capsules have been approved in many countries since 1998 (Entocort CIR, Budenofalk). Structure and properties Budesonide (C25H34O6, Mr = 430.5 g/mol) is a racemate and exists as a white, crystalline, odorless, tasteless powder that is practically insoluble in water. Effects Budesonide (ATC R03BA02) has anti-inflammatory, antiallergic, and immunosuppressive properties. The effects are … Budesonide Capsules
