Products Meloxicam was commercially available in tablet form (Mobicox). It was approved in many countries since 1995. It was discontinued from distribution in 2016. Structure and properties Meloxicam (C14H13N3O4S2, Mr = 351.4 g/mol) belongs to the oxicams and is a thiazole and a benzothiazine derivative. It exists as a yellow powder that is practically insoluble … Meloxicam
Products Firocoxib is commercially available as chewable tablets for dogs and as a paste for administration in horses. It has been approved in many countries since 2004. Structure and properties Firocoxib (C17H20O5S, Mr = 336.4 g/mol) is a furanone derivative. Like other COX-2 inhibitors, it has a V-shaped structure that allows binding to the Active … Firocoxib
Products Methotrexate is commercially available as a solution for parenteral use and in tablet form. See also under methotrexate prefilled syringe (low-dose). Structure and properties Methotrexate (C20H22N8O5, Mr = 454.44 g/mol) is a dicarboxylic acid that exists as a yellow to orange crystalline powder that is virtually insoluble in water. Methotrexate was developed as a … Methotrexate: Drug Effects, Side Effects, Dosage and Uses
Products Cimetidine was commercially available in the form of film-coated tablets (Tagamet). Currently, there are no longer any human medicines registered with the active ingredient in many countries. Cimetidine was developed in the 1960s and 1970s under the leadership of Sir James Black as the first wirsktoff from the group of H2 receptor antagonists and … Cimetidine
Products Nicorandil is commercially available in tablet form (Dancor). It has been approved in many countries since 1993. Structure and properties Nicorandil (C8H9N3O4, Mr = 211.2 g/mol), like nitroglycerin, is an organic nitrate. It is a combination of the vitamin nicotinamide with an ethyl nitrate. Effects Nicorandil (ATC C01DX16) has vasodilator, antihypertensive, and cardioprotective properties. … Nicorandil
Products Proton pump inhibitors (PPIs) are commercially available in many countries in the form of film-coated tablets, MUPS tablets, capsules, as granules for preparation of an oral suspension, and as injectable and infusion preparations. The first active ingredient from this group to be approved in many countries was omeprazole (Antra, Losec), developed by Astra in … Proton Pump Inhibitors
Products Rabeprazole is commercially available in the form of film-coated tablets (Pariet, generic). It has been approved in many countries since 1999. Generic versions have been available since 2012. Structure and properties Rabeprazole (C18H21N3O3S, Mr = 359.4 g/mol) is a benzimidazole and pyridine derivative and a racemate. It is present in drugs as rabeprazole sodium, … Rabeprazole
Products Diclofenac is commercially available in the form of tablets, capsules, soft capsules (liquid caps), dragées, drops, suppositories, as a solution for injection, gel, patches, and eye drops (Voltaren, generics), among others. The analgesic has been approved in many countries since 1974. This article refers to peroral use. For more information, see also diclofenac gel, … Diclofenac: Drug Effects, Side Effects, Dosage and Uses
Products Famotidine is not commercially available in many countries. In Germany and other countries, it is available in the form of film-coated tablets. Structure and properties Famotidine (C8H15N7O2S3, Mr = 337.4 g/mol) exists as a white to yellowish-white crystalline powder or as crystals and is very sparingly soluble in water. It is a thiazole derivative … Famotidine
Products Ibuprofenarginate is commercially available as film-coated tablets and as granules (Dolo-Spedifen, Spedifen). It has been approved in many countries since 1990. Structure and properties Ibuprofenarginate (C19H32N4O4, Mr = 380.5 g/mol) is the salt of the natural amino acid arginine with the analgesic ibuprofen. Ibuprofen is negatively charged and arginine is positively charged. Ibuprofen is … Ibuprofenarginate
Products Ibuprofen lysinate is commercially available in the form of film-coated tablets and granules (e.g., Algifor-L, Ibufen-L, generics), among others. It has been approved in many countries since 1979. Structure and properties Ibuprofen lysinate (C19H32N2O4, Mr = 352.5 g/mol) is the salt of the natural amino acid lysine with the analgesic ibuprofen. Ibuprofen is negatively … Ibuprofen Lysinate
Products Ranitidine was commercially available in the form of film-coated tablets, effervescent tablets, and as a solution for injection and had been approved since 1981 (Zantic, generic). Currently, drugs containing ranitidine are no longer available in many countries. Starting in 1996, tablets for self-medication with 75 mg were released. However, they are now also no … Ranitidine: Drug Effects, Side Effects, Dosage and Uses
