Dihydroergotamine

Products The marketing of medicinal products containing dihydroergotamine has been discontinued in many countries (e.g., Dihydergot tablets and nasal spray, Ergotonin, Effortil plus, Old Tonopan, and others). The approval of Dihydergot tablets was cancelled on February 1, 2014, because the benefits no longer outweighed the potential risks, according to drug regulators. Structure and properties Dihydroergotamine … Dihydroergotamine

Diltiazem

Products Diltiazem is commercially available in tablet and capsule form (Dilzem, generic). It has been approved in many countries since 1982. Structure and properties Diltiazem (C22H26N2O4S, Mr = 414.52 g/mol) is a benzothiazepine derivative. It is present in drugs as diltiazem hydrochloride, a white crystalline powder with a bitter taste that is readily soluble in … Diltiazem

Risedronate

Products Risedronate is available as weekly 35 mg tablets and as 30 mg tablets (Actonel, generic). Actonel 5 mg and 75 mg tablets are off-label in many countries. Risedronate has been approved since 2000. Generic versions went on sale in 2012. Structure and properties Risedronate (C7H10NO7P2Na – 2.5 H2O, Mr = 350.1 g/mol) is a … Risedronate

Rivastigmine

Products Rivastigmine is commercially available as capsules, oral solution, and transdermal patch (Exelon, generics). It has been approved in many countries since 1997. Structure and properties Rivastigmine (C14H22N2O2, Mr = 250.3 g/mol) is a phenyl carbamate. It exists in the oral forms as rivastigmine hydrogenotartrate, a white crystalline powder that is very soluble in water. … Rivastigmine

Rivipansel (GMI-1070)

Products Rivipansel is currently in clinical development at GlycoMimetics and Pfizer. The drug is not yet commercially available. Structure and properties Rivipansel (C58H74N6O31S3, Mr = 1447.4 g/mol) is a glycomimetic developed by the research group led by Prof. Beat Ernst at the Institute of Molecular Pharmacy, University of Basel, in collaboration with GlycoMimetics. Effects Rivipansel … Rivipansel (GMI-1070)

Rizatriptan

Products Rizatriptan is commercially available in tablet and lingual (melting) tablet form (Maxalt, generics). It has been approved in many countries since 2000. Generic versions went on sale in 2015. Structure and properties Ritatriptan (C15H19N5, Mr = 269.3 g/mol) is present in drugs as rizatriptan benzoate, a white crystalline powder that is soluble in water. … Rizatriptan

Mercury

Application Mercury (Hydrargyrum, Hg) and its compounds are rarely used in pharmacy today because of their toxicity and adverse effects. An exception is alternative medicine, in which mercury is also called mercurius (e.g., Mercurius solubilis, Mercurius vivus). The English name is Mercury or Quicksilver. In the 20th century, mercury compounds were still widely used and … Mercury

Quinapril

Products Quinapril is commercially available in the form of film-coated tablets as a monopreparation (Accupro) and as a fixed combination with hydrochlorothiazide (Accuretic, Quiril comp). It has been approved in many countries since 1989. Generic versions are registered. Structure and properties Quinapril (C25H30N2O5, Mr = 438.5 g/mol) is present in drugs as quinapril hydrochloride, a … Quinapril

Quinisocaine

Products Quinisocaine was commercially available in many countries as an ointment (isoquinol) since 1973. In 2013, distribution was discontinued. Structure and properties Quinisocaine (C17H24N2O, Mr = 272.4 g/mol) is an isoquinoline derivative and is present in the drug as quinisocaine hydrochloride. It is classified as an amide-type local anesthetic. Effects Quinisocaine (ATC D04AB05) has local … Quinisocaine

Misoprostol

Products Misoprostol tablets for medication abortion were approved in many countries in 2015 (MisoOne). This article refers to abortion. In addition, other drugs exist with other indications (gastric protection, induction of labor). Structure and properties Misoprostol (C22H38O5, Mr = 382.5 g/mol) is a synthetic derivative of prostaglandin E1 and exists as a mixture of two … Misoprostol

Indigocarmine

Products Indigocarmine is available as a pure substance in specialized stores. Structure and properties Indigocarmine (C16H8N2Na2O8S2, Mr = 466.4 g/mol) exists as a blue powder that is soluble in water. The solutions are either yellow or blue depending on the pH. Areas of application Dye for many drugs (e.g. Rohypnol, Viagra, Truvada). Dye for food … Indigocarmine

Indinavir

Products Indinavir is commercially available in capsule form (Crixivan). It has been approved in many countries since 1996. Structure and properties Indinavir (C36H47N5O4, Mr = 613.8 g/mol) is present in drugs as indinavir sulfate, a white crystalline powder that is very soluble in water. Effects Indinavir (ATC J05AE02) has antiviral properties. The effects are due … Indinavir