Products Sulfasalazine is commercially available as tablets and as dragées with an enteric coating (salazopyrin, salazopyrin EN, some countries: azulfidine, azulfidine EN, or RA). It has been approved in many countries since 1950. EN stands for enteric coated and RA for Rheumatoid Arthritis. EN dragées have a coating to prevent irritation and improve gastric tolerance. … Sulfasalazine: Drug Effects, Side Effects, Dosage and Uses
Products Codeine is available alone or in combination with other active ingredients in the form of tablets, effervescent tablets, capsules, dragées, syrups, drops, bronchial pastilles, and as suppositories. It is also combined fixedly with acetaminophen for the treatment of pain (see under codeine acetaminophen). Structure and properties Codeine (C18H21NO3, Mr = 299.36 g/mol) is -methylated … Codeine: Drug Effects, Side Effects, Dosage and Uses
Products Beta2-sympathomimetics are usually commercially available as inhalation preparations (powders, solutions) administered with an inhaler, for example, metered-dose inhaler, diskus, Respimat, Breezhaler, or Ellipta. There are few drugs on the market that can be given perorally. Structure and properties Beta2-sympathomimetics are structurally related to the natural ligands epinephrine and norepinephrine. They may exist as racemates … Beta2-Sympathomimetics
Products Polihexanide is commercially available as a solution and concentrate (Lavasept). It has been approved in many countries since 1991. Structure and properties Polihexanide (C8H19N5, Mr = 185.3 g/mol) is a biguanide derivative. Effects Polihexanide (ATC D08AC05) has bactericidal and fungicidal properties. Indications For antiseptic wound treatment and prophylaxis of bone and soft tissue infections. … Polihexanide
Products Prazepam is commercially available in tablet form (Demetrin). It has been approved in many countries since 1977. Structure and properties Prazepam (C19H17ClN2O, Mr = 324.8 g/mol) exists as a white crystalline powder that is practically insoluble in water. It carries a cyclopropyl group. Effects Prazepam (ATC N05BA11) has antianxiety, sedative, relaxant, and depressant properties. … Prazepam
Products Omalizumab is commercially available as a powder and solvent for solution for injection (Xolair). It has been approved in many countries since 2006. Structure and properties Omalizumab is a recombinant, humanized monoclonal antibody with a molecular weight of approximately 149 kDa. Effects Omalizumab (ATC R03DX05) has antiallergic and antiasthmatic properties. The effects are based … Omalizumab
Products Medicines containing tolbutamide are no longer available in many countries. Structure and properties C12H18N2O3S, 270.34 g/mol
Products Duloxetine is commercially available in the form of capsules (Cymbalta, generic). It has been approved in many countries since 2005. Structure and properties Duloxetine (C18H19NOS, Mr = 297.4 g/mol) is present in drugs as pure -duloxetine hydrochloride, a white to light brown powder that is sparingly soluble in water. Effects Duloxetine (ATC N06AX21) has … Duloxetine
Products Haloperidol is commercially available as tablets, drops (Haldol), and as a solution for injection (Haldol, Haldol decanoas). It has been approved in many countries since 1960. Structure and properties Haloperidol (C21H23ClFNO2, Mr = 375.9 g/mol) is a derivative of pethidine, which is itself derived from atropine. It has structural similarity to loperamide. Haloperidol exists … Haloperidol
Products Balovaptan is in clinical development and is not yet commercially available. In January 2018, the compound received the FDA’s. Structure and properties Balovaptan (C22H24ClN5O, Mr = 409.9 g/mol) structurally belongs to the benzodiazepines. Effects Balovaptan improves social interaction and communication in patients with autism. The effects are due to antagonism at vasopressin-1a receptors. Vasopressin … Balovaptan
Products Apremilast is commercially available in the form of film-coated tablets (Otezla). It was approved in the United States in 2014 and in many countries and the EU in 2015. Structure and properties Apremilast (C22H24N2O7S, Mr = 460.5 g/mol) is a dioxoisoindole acetamide derivative. Effects Apremilast (ATC L04AA32) has immunomodulatory and anti-inflammatory properties. The effects … Apremilast
Products Velaglucerase alfa is commercially available as a powder for the preparation of an infusion solution (Vpriv). It has been approved in many countries since 2011. Structure and properties Velaglucerase alfa is an enzyme and glycoprotein with 497 amino acids and the same sequence as natural glucocerebrosidase. Glycosylation with mannose results in velaglucerase alfa being … Velaglucerase Alfa
