Prolongation of the QT Interval

Symptoms Drug-induced prolongation of the QT interval can rarely lead to severe arrhythmias. This is polymorphic ventricular tachycardia, known as torsade de pointes arrhythmia. It can be seen on the ECG as a wave-like structure. Due to the dysfunction, the heart cannot maintain blood pressure and can only pump insufficient blood and oxygen to the … Prolongation of the QT Interval

Abiraterone Acetate

Products Abiraterone is commercially available in the form of film-coated tablets (Zytiga). It has been approved in many countries since 2011. Structure and properties Abiraterone acetate (C26H33NO2, Mr = 391.5 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug and is rapidly biotransformed in the body to … Abiraterone Acetate

Bisacodyl

Products Bisacodyl is commercially available in the form of enteric-coated tablets (dragées) and suppositories (Dulcolax, generics). It has been approved in many countries since 1957. Structure and properties Bisacodyl (C22H19NO4, Mr = 361.39 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a diphenylmethane and triarylmethane derivative. Bisacodyl is … Bisacodyl

Ammonium Chloride

Products In many countries, human medicines with ammonium chloride as the active ingredient are no longer on the market. The salt is an ingredient in Mixtura solvens (Dissolving Mixture PH) and licorice. It used to be included in Bisolvon Linctus syrup along with bromhexine. In some countries, expectorants are available. Structure and properties Ammonium chloride … Ammonium Chloride

Cascara Bark

Stem plant The parent plant of arnzeidroge is the American sloth tree D.C. of the buckthorn family. Medicinal drug Cascara bark (Rhamni purshiani cortex) is used as a medicinal drug. It consists of the dried whole or crushed bark of D.C. ( (D.C.) A. Gray) (PhEur). The pharmacopoeia requires a minimum content of hydroxyanthracene glycosides. … Cascara Bark

Caspofungin

Products Caspofungin must be administered as an infusion solution because of its low oral bioavailability (Cancidas, generics). It has been approved in many countries since 2002 and was the first member of the echinocandins. Structure and properties Caspofungin is present in drugs as caspofungin diacetate (C52H88N10O15 – 2C2H4O2, Mr = 1213.42 g/mol), a hygroscopic white … Caspofungin

Rhubarb

Stem plant Baillon, Polygonaceae, rhubarb. Medicinal drug Rhei radix – Rhubarb root: Rhubarb root consists of the dried, whole or cut parts of L., Baillon, of hybrids of the two species, or of a mixture. The underground parts are often divided. The drug is stripped of the stem and largely of the outer bark with … Rhubarb

Coffee

Products Dried coffee beans, coffee powder, coffee capsules and other products are available in grocery stores. Stem plant The parent plant is the coffee shrub or coffee tree from the Rubiaceae family (redbud family). The two main species are for Arabica coffee and for Robusta coffee. is also called. Medicinal drug The so-called coffee beans … Coffee

Potassium Health Benefits

Products Potassium is commercially available, among other things, in the form of effervescent tablets (so-called effervettes), as sustained-release dragées and sustained-release tablets (e.g., Kalium Hausmann, KCl-retard, Plus Kalium). It is also contained in sports drinks such as Isostar or Sponser. The dose is usually expressed in millimoles (mmol) or milliequivalents (mEq): 1 mmol = 39.1 … Potassium Health Benefits

Thiazide Diuretics

Products Thiazide diuretics are commercially available in tablet form. Chlorothiazide (Diuril) and the closely related and more potent hydrochlorothiazide were the first of this group to enter the market in the 1950s (Switzerland: Esidrex, 1958). However, other related thiazide-like diuretics are available (see below). In English, we speak of (thiazide diuretics) and (thiazide-like diuretics). Numerous … Thiazide Diuretics