Products Beta2-sympathomimetics are usually commercially available as inhalation preparations (powders, solutions) administered with an inhaler, for example, metered-dose inhaler, diskus, Respimat, Breezhaler, or Ellipta. There are few drugs on the market that can be given perorally. Structure and properties Beta2-sympathomimetics are structurally related to the natural ligands epinephrine and norepinephrine. They may exist as racemates … Beta2-Sympathomimetics
Products Olodaterol was approved in many countries in 2014 as a solution for inhalation (Striverdi). In 2016, a fixed-dose combination with tiotropium bromide was also marketed (Spiolto). Both drugs are administered with the Respimat. Respimat The Respimat is a new inhalation device that releases a visible spray, or aerosol. The droplets are fine and move … Olodaterol
Products Sorbitol is found alone or in combination with other active ingredients in various laxatives (e.g., Pursana). It is also marketed as an open product and as a solution. Structure and properties Sorbitol (C6H14O6, Mr = 182.2 g/mol) exists as D-sorbitol, a white crystalline powder with a sweet taste that is very soluble in water. … Sorbitol
Products Blinatumomab is commercially available as an infusion product (Blincyto). It has been approved in the United States since 2014, in the EU since 2015, and in many countries since 2016. Structure and properties Blinatumomab is an antibody construct (fusion protein) of 504 amino acids with a molecular weight of approximately 54 kDa. It consists … Blinatumomab
Products Anidulafungin is commercially available as a powder for the preparation of an infusion solution (Ecalta, generics). It has been approved in many countries since 2009. Structure and properties Anidulafungin (C58H73N7O17, Mr = 1140.3 g/mol) is a cyclic lipopeptide. It is a semisynthetic echinocandin obtained from a fermentation product of . It exists as a … Anidulafungin
Products Fondaparinux is commercially available as a solution for injection (Arixtra). It has been approved in many countries since 2002. Structure and properties Fondaparinux (C31H43N3Na10O49S8, Mr = 1728 g/mol) is a synthetic pentasaccharide belonging to the class of glycosaminoglycans. It is present in the drug as fondaparinux sodium. Effects Fondaparinux (ATC B01AX05) has antithrombotic properties. … Fondaparinux
Products Formoterol is commercially available in the form of capsules for inhalation (Foradil) and as a powder inhaler (Oxis). Furthermore, combination products with budesonide (Symbicort Turbuhaler, Vannair Dosieraerosol) and fluticasone propionate are available (Formoterol Dosieraerosol). Formoterol is also combined with beclometasone fixed, see under beclometasone and formoterol (Foster). Furthermore, in 2020, a fixed combination with … Formoterol
Products Sodium sulfate is available in pharmacies and drugstores as open goods. Structure The European Pharmacopoeia contains two monographs. Glauber’s salt proper is sodium sulfate decahydrate. Sodium sulfate decahydrate Glauber’s salt Na2SO4 – 10 H2O Natrii sulfas decahydricus Anhydrous sodium sulfate Na2SO4 Natrii sulfas anhydricus Commercially available, in addition to the two salts mentioned, is … Sodium Sulfate (Glauber’s Salt)
Products Sodium picosulfate is commercially available in the form of tablets, soft capsules (pearls), and drops (e.g., Laxoberon, Dulcolax Picosulfate). It has been approved in many countries since 1973. Structure and properties Sodium picosulfate (C18H13NNa2O8S2, Mr= 481.41 g/mol) is structurally closely related to bisacodyl. The difference is that it is esterified with sulfuric acid instead … Sodium Picosulfate
Symptoms Infection with norovirus manifests as gastroenteritis with diarrhea without blood in the stool and/or with violent, even explosive vomiting. Vomiting is more common in children. Furthermore, accompanying symptoms such as nausea, bloating, abdominal pain, abdominal cramps, muscle pain, headache, and mild fever may occur. An asymptomatic course is also possible. The duration of the … Norovirus
Products Glycerol (synonym: glycerol) is contained in numerous drugs as a pharmaceutical excipient. As an active ingredient, it is mainly used as a laxative in the form of suppositories or as an enema (e.g., Bulboid). Structure and properties Glycerol or propane-1,2,3-triol (C3H8O3, Mr = 92.1 g/mol) is a colorless, clear, fatty-feeling, syrupy, very hygroscopic liquid … Glycerol
Products Torasemide is commercially available in tablet form (Torem, generic). It has been approved in many countries since 1993. Structure and properties Torasemide (C16H20N4O3S, Mr = 348.4 g/mol) exists as a white powder that is practically insoluble in water. It is a pyridine-sulfonylurea derivative. Torasemide differs structurally from its precursor furosemide (Lasix, generics), a sulfonamide. … Torasemide
