Products Golimumab is commercially available as a solution for injection (Simponi). It was approved in many countries in 2010. Structure and properties Golimumab (Mr = 150 kDa) is a human IgG1κ-monoclonal antibody. Effects Golimumab (ATC L04AB06) has selective immunosuppressive and anti-inflammatory properties. The effects are based on binding to the soluble and membrane-bound proinflammatory cytokine … Golimumab
Products TNF-α inhibitors are commercially available as injectable and infusion preparations. Infliximab (Remicade) was the first agent from this group to be approved in 1998, and in many countries in 1999. Biosimilars of some representatives are now available. Others will follow in the next few years. This article refers to biologics. Small molecules can also … TNF-Α Inhibitors
Products Bextra film-coated tablets are no longer on the market in many countries. Approval was withdrawn in April 2005 because rare severe skin reactions had occurred during treatment (see below). Structure and properties Valdecoxib (C16H14N2O3S, Mr = 314.4 g/mol) is a phenylisoxazole and a benzenesulfonamide derivative. It has a V-shaped structure with which it binds … Valdecoxib
Products Fish oil is available in the form of soft capsules from various suppliers, such as Alpinamed, Biorganic, Burgerstein or Phytomed. Fish oil can also be supplied to the body through regular consumption of fish. At least one to two fish meals per week are recommended. Structure and properties Fish oil is a purified, winterized … Fish Oil
Products Omega-3 fatty acids are usually administered in the form of softgels. Oils for oral use are also available. Some foods are rich in omega-3 fatty acids (see below). Structure and properties The most important omega-3 fatty acids include eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). They are polyunsaturated and long-chain fatty acids (PUFA: PolyUnsaturated … Omega 3 Fatty Acids Health Benefits
Products COX-2 inhibitors (coxibe) are commercially available in the form of film-coated tablets and capsules. The first representatives from this group to be approved in many countries were celecoxib (Celebrex, USA: 1998) and rofecoxib (Vioxx, off label) in 1999. At that time, they rapidly developed into blockbuster drugs. However, due to adverse effects, several drugs … COX-2 Inhibitor
Products MSM is commercially available in the form of tablets, capsules and powder, among others, as a food supplement without indications. It is also applied externally, for example, as a cream and balm. Medicines containing MSM have not yet been approved. Structure and properties MSM (C2H6O2S, Mr = 94.1 g/mol) is a low molecular weight … MSM (Methylsulfonylmethane)
Products Tofacitinib was approved in the United States in November 2012, in many countries in 2013, and in the EU in 2017 in film-coated tablet form (Xeljanz). The European Medicines Agency initially rejected the approval in April 2013. However, baricitinib was approved. In the United States, additional sustained-release film-coated tablets are available that are taken … Tofacitinib
Under the term rheumatism different disease patterns are summarized, which is why the term rheumatoid diseases is also used. The most common disease here is rheumatoid arthritis, which is associated with the typical joint complaints. So-called rheumatic nodules form, preferably on the hands. Muscle pain, slight fever and inflammatory diseases of other organs can also … Homeopathy to treat rheumatism
Is there a suitable complex agent? Active ingredients: The GELENK ALBIN drops to be taken contain five different homeopathic active ingredients. To it effect belong: The effect of the complex means is based on an effective combination of numerous hom?opathischer preparations, which can lindern complaints with rheumatism. The complex remedy has a pain-relieving and modulating … Is there a suitable complex agent? | Homeopathy to treat rheumatism
Treatment of the disease only with homeopathy or only as supportive therapy? In the case of rheumatism, appropriate treatment should be carried out in consultation with a doctor, as the disease can spread to numerous organs and other joints. However, homeopathic preparations can always be used to support the treatment. An appropriate consultation with the … Treatment of the disease only with homeopathy or only as supportive therapy? | Homeopathy to treat rheumatism
Which home remedies can help me? There are various home remedies that can help with rheumatism. For example incense belongs to it, which can be acquired as finished preparation in the pharmacy. The essential oils contained in it have a reducing effect on the pain, as well as the signs of the inflammatory process and … Which home remedies can help me? | Homeopathy to treat rheumatism
