Products Imiglucerase is commercially available as a powder for the preparation of an infusion solution (Cerezyme). It has been approved in many countries since 1999. Structure and properties Imiglucerase is an enzyme produced by biotechnological methods. The glycoprotein consists of 497 amino acids. The sequence differs in one amino acid from the natural acid beta-glucocerebrosidase. … Imiglucerase
Products Alpha-galactosidase is commercially available as a dietary supplement or medical device in some countries, for example, Germany and the United States. It is also combined with other enzymes. Structure and properties Alpha-galactosidase is an enzyme that is usually extracted from fungi like. Effects Alpha-galactosidase cleaves indigestible carbohydrates, which are found, for example, in legumes, … Alpha-Galactosidase
Products Imipenem is commercially available as an infusion preparation and fixed combination with cilastatin (Tienam, generics). Imipenem was approved in many countries in 1985 as the first member of the carbapenems. Structure and properties Imipenem (C12H17N3O4S, Mr = 299.3 g/mol) is present in drugs as imipenem monohydrate, a white or pale yellow powder that is … Imipenem
Effects Alpha-glucosidase inhibitors (ATC A10BF) have antidiabetic properties: Glucose is released more slowly in the gut and absorbed more slowly into the blood Decrease the rise in blood glucose after meals and blood sugar fluctuations. Do not cause hypoglycemia as monotherapy Mechanism of action The action is based on the inhibition of intestinal enzymes (alpha-glucosidases) … Alpha-Glucosidase Inhibitors
Products Human alpha1-proteinase inhibitor was approved in many countries in 2016 as a powder and solvent for the preparation of an intravenous infusion solution (Respreeza, USA: Zemaira). It has been approved in the United States since 2003 and in the EU since 2015. Structure and properties Human alpha1-proteinase inhibitor is a glycoprotein derived from human … Human Alpha1-Proteinase Inhibitor
Products Alpha blockers are available in many countries in the form of tablets, sustained-release tablets, capsules, and sustained-release capsules. The most commonly prescribed today is tamsulosin (Pradif T, generic). Alpha blocker is short for alpha1-adrenoreceptor antagonist. Structure and properties The first alpha blockers-alfuzosin, doxazosin, and terazosin-were developed as derivatives of quinazoline: Effects Alpha blockers (ATC … Alpha Blocker
Products Alprazolam is commercially available as tablets, sustained-release tablets, and sublingual tablets (Xanax, generics). It has been approved in many countries since 1980. “Xanax” is a palindrome and remains the same when read forwards or backwards. Structure and properties Alprazolam (C17H13ClN4, Mr = 308.7 g/mol) exists as a white crystalline powder that is practically insoluble … Alprazolam
Products Flecainide is commercially available as tablets and as a solution for injection (Tambocor). It has been approved in many countries since 1984. Structure and properties Flecainide (C17H20F6N2O3, Mr = 414.3 g/mol) is present in drugs as flecainide acetate, a white, crystalline, and very hygroscopic powder that is soluble in water. It is an amide-type … Flecainide
Products Flibanserin (Addyi) was approved in the United States in 2015 in the form of film-coated tablets. The drug has not yet been registered in many countries. Flibanserin was originally developed at Boehringer Ingelheim as an antidepressant. It was marketed in the United States by Sprout Pharmaceuticals. Structure and properties Flibanserin (C20H21F3N4O, Mr = 390.4 … Flibanserin
Products Florfenicol is commercially available as a solution for injection for animals. It has been approved in many countries since 1996. Structure and properties Florfenicol (C12H14Cl2FNO4S, Mr = 358.2 g/mol) is structurally closely related to chloramphenicol. Effects Florfenicol (ATCvet QJ01BA90) has bacteriostatic properties. The effects are due to inhibition of bacterial protein synthesis. Indications For … Florfenicol
Products Flubendazole is commercially available as a paste, drug premix, and chewable tablets for animals. It has been approved in many countries since 1984. Human drugs are not currently registered. Structure and properties Flubendazole (C16H12FN3O3, Mr = 313.3 g/mol) is a fluorinated benzimidazole derivative. It is a white powder that is practically insoluble in water … Flubendazole
Products Flucloxacillin is commercially available in capsule form and as an injectable (floxapen, generic). It has been approved in many countries since 1972. Structure and properties Flucloxacillin (C19H17ClFN3O5S, Mr = 453.9 g/mol) is present in drugs as the sodium salt flucloxacillin sodium, a white, crystalline, and hygroscopic powder that is readily soluble in water. Flucloxacillin … Flucloxacillin