Products In many countries, finished medicines containing cocaine are currently no longer commercially available. However, they can be prepared as an extemporaneous prescription in a pharmacy. Cocaine is subject to the Narcotics Act and requires an aggravated prescription, but it is not banned as a drug. It is also sold as an illegal narcotic on … Cocaine: Drug Effects, Side Effects, Dosage and Uses
Products Ketamine is commercially available as a solution for injection (Ketalar, generic). It has been approved in many countries since 1969. Esketamine nasal spray was approved in 2019 (Switzerland: 2020) for the treatment of treatment-resistant depression (see there). Structure and properties Ketamine (C13H16ClNO, Mr = 237.7 g/mol) is a cyclohexanone derivative derived from phencyclidine (“angel … Ketamine: Drug Effects, Side Effects, Dosage and Uses
Products Methamphetamine is no longer registered as a drug in many countries. Pervitin has been out of commerce for some time. Methamphetamine is one of the narcotics and is subject to more stringent prescription requirements, but it is not a banned substance. In principle, medicines could be prepared in pharmacies as a magisterial prescription. In … Methamphetamine
Caniphedrine The alkaloid L-ephedrine is found along with other alkaloids in plants of the genus Ephedra (e.g., Stapf, Ephedraceae). The herb has been used in Chinese medicine under the name Ma Huang for over 5000 years. In the 16th century pharmacopoeia Pentsao Kang Mu by Li Shih-Chen, it is recommended as a circulatory stimulant, diaphoretic, … Cave Canem: Caniphedrine
Products Amfepramone is commercially available in the form of capsules (e.g., Regenon). The drug is not registered in many countries. Structure and properties Amfepramone (C 13 H 19 NO, M r = 205.3 g/mol) is structurally related to cathinone. Effects Amfepramone (ATC A08AA03) has indirect sympathomimetic, appetite suppressant, and antiadipose properties. The effects are due … Amfepramone
Products Isoprenaline was newly approved in many countries in the fall of 2010 as a solution for injection/concentrate for the preparation of an infusion solution (Isuprel). Structure and properties Isoprenaline (C11H17NO3, Mr = 211.3 g/mol) is a methyl derivative of epinephrine and a racemate. It is present in the drug as isoprenaline hydrochloride, a white … Isoprenaline
Products Hexoprenaline is commercially available as a solution for injection (Gynipral). It has been approved in many countries since 1984. Approval for the tablets was revoked on Dec. 31, 2013. This due to the potential cardiovascular side effects that may occur in the mother and child. Structure and properties Hexoprenaline (C22H32N2O6, Mr = 420.5 g/mol) … Hexoprenaline
Products Mescaline, peyote, and San Pedro are among the banned narcotics in many countries and are therefore generally not legally available. Structure and properties Mescaline (C11H17NO3, Mr = 211.3 g/mol) is a trimethoxy-phenylethylamine derivative with a bitter taste (3,4,5-trimethoxyphenylethylamine). Mescaline is structurally related to catecholamines such as epinephrine and to ecstasy, among others. Origin Mescaline … Mescaline
Products Methylphenidate is commercially available in many countries in the form of tablets, film-coated tablets, sustained-release tablets, and sustained-release capsules (e.g., Ritalin, Concerta, Medikinet, Equasym, generics). It has been approved since 1954. The drug is subject to strict control as a narcotic and is available only by prescription. The isomer dexmethylphenidate (Focalin XR) is also … Methylphenidate: Drug Effects, Side Effects, Dosage and Uses
Products Dronabinol is an anesthetic. The Federal Office of Public Health may grant an exemption for limited medical use. Pharmacies can make dronabinol preparations themselves as an extemporaneous prescription or have them made by contract manufacturing. There are two provisions in the new formulary: Oily dronabinol drops 2.5% (NRF 22.8). Dronabinol capsules 2.5 mg, 5 … Dronabinol
Products LABA is an acronym for , which means long-acting beta agonists (sympathomimetics). LABAs are mainly marketed as inhaled preparations (powders, solutions) administered with an inhaler such as a metered-dose inhaler, diskus, respimat, breezhaler, or ellipta. Some may also be given perorally. Salmeterol and formoterol were the first agents from this group to be approved … LABA
Products Xylometazoline is commercially available in the form of nasal sprays and as nasal drops (Otrivin, generics, combination products, for example with dexpanthenol). It was developed at Ciba and has been approved in many countries since 1958. Structure and properties Xylometazoline is present in drugs as xylometazoline hydrochloride (C16H24N2 – HCl, Mr = 280.8 g/mol), … Xylometazoline
